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生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
RCK107, monoclonal
物種活性
rat, pig, human, canine
製造商/商標名
Chemicon®
技術
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同型
IgG3
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... KRT14(3861)
rat ... Krt14(287701)
一般說明
细胞角蛋白是中间丝蛋白的一个亚家族,其特征在于显著的生化多样性,在上皮组织中由至少20种不同的多肽代表。它们的分子量范围为40 kDa至68 kDa,等电pH值范围为4.9-7.8,单个细胞角蛋白多肽为1-20。人体内的各种上皮细胞通常表达细胞角蛋白,其不仅是上皮类型的特征,而且还与上皮内的成熟或分化程度有关。细胞角蛋白亚型表达模式越来越多地用于区分不同类型的上皮恶性肿瘤。
特異性
细胞角蛋白14.MAB3232与分层和组合上皮的基底细胞区室反应。与在喉,食道,气管,膀胱,前列腺,子宫颈,阴道,乳腺腺泡,皮肤和汗腺的基底细胞中表达的细胞角蛋白14反应。
免疫原
TR146上皮细胞的细胞骨架制备。
應用
使用经验证可用于FC、WB、IC、IH的抗细胞角蛋白14抗体(克隆RCK107)检测细胞角蛋白14。
研究子类别
细胞角蛋白
细胞角蛋白
研究类别
细胞结构
细胞结构
蛋白质印迹
冷冻组织切片的免疫组化。
免疫细胞化学
流式细胞术
最佳工作稀释度必须由最终用户进行确定。
冷冻组织切片的免疫组化。
免疫细胞化学
流式细胞术
最佳工作稀释度必须由最终用户进行确定。
外觀
含 0.1% 叠氮化钠的缓冲液液体。
形式:纯化
儲存和穩定性
以未稀释等分试样保存于-20°C下6个月。应避免反复冻/融循环。
其他說明
浓度:请参考批次特异性浓缩物的分析证书。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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