推荐产品
品質等級
包裝
pkg of 2 × 1 mL
製造商／商標名
PureProteome
技術
depletion: suitable (serum)
immunoprecipitation (IP): suitable
protein purification: suitable
粒徑
10 μm
容量
1.5-2.5 μg/μL, suspension binding capacity (rabbit IgG)
運輸包裝
wet ice
一般說明
PureProteome™蛋白A磁珠系统是一个强大的系统，通过最大化回收率和消除可变性来帮助研究人员纯化蛋白质。
應用
PureProteome™蛋白A磁珠系统可用于：
- 血清去除和免疫沉淀中的蛋白纯化，以及加入细胞裂解物中用于通过蛋白质印迹法分析结合蛋白
- 磁珠结合实验
- 免疫沉淀细胞裂解物和抗体，以便进行ATP酶活力检测
法律資訊
PureProteome is a trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Kris Wilson et al.
Journal of biomolecular screening, 20(2), 292-298 (2014-10-10)
Human kynurenine 3-monooxygenase (KMO) is emerging as an important drug target enzyme in a number of inflammatory and neurodegenerative disease states. Recombinant protein production of KMO, and therefore discovery of KMO ligands, is challenging due to a large membrane targeting
Konstantin Chegaev et al.
ACS medicinal chemistry letters, 8(3), 361-365 (2017-03-25)
Nitric oxide (NO) release from a suitable NO photodonor (NOP) can be fine-tuned by visible light stimuli at doses that are not toxic to cells but that inhibit several efflux pumps; these are mainly responsible for the multidrug resistance of
Fei-Yun Chen et al.
The Journal of cell biology, 218(9), 3002-3018 (2019-08-08)
The BH3-only pro-apoptotic protein BIK is regulated by the ubiquitin-proteasome system. However, the mechanism of this regulation and its physiological functions remain elusive. Here, we identify Cul5-ASB11 as the E3 ligase targeting BIK for ubiquitination and degradation. ER stress leads
Holger Laux et al.
Biotechnology and bioengineering, 115(10), 2530-2540 (2018-05-20)
An increasing number of nonantibody format proteins are entering clinical development. However, one of the major hurdles for the production of nonantibody glycoproteins is host cell-related proteolytic degradation, which can drastically impact developability and timelines of pipeline projects. Chinese hamster
Thibaut Hacquard et al.
Cell reports, 39(2), 110671-110671 (2022-04-14)
RNA silencing is a conserved mechanism in eukaryotes involved in development and defense against viruses. In plants, ARGONAUTE1 (AGO1) protein plays a central role in both microRNA- and small interfering RNA-directed silencing, and its expression is regulated at multiple levels.
商品
The possible causes and potential remedies for challenges encountered in the immunoprecipitation-Western blot technique, which consists of cell lysis, formation of the antibody-antigen (immune) complex, precipitation of the immune complexes, and analysis by Western blotting.
通过 PureProteome™ Protein A 和 Protein G 磁珠，可利用 KingFisher Duo 磁珠纯化仪快速、可重现地纯化免疫球蛋白 (IgG)。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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