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生物源
rabbit
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性（以同源性預測）
all
技術
ChIP: suitable
RIP: suitable
dot blot: suitable
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
N6-甲基腺苷（m6A），或腺苷N6位的甲基化，是RNA的一种转录后修饰。 由于分析方法的缺乏，人们对N6-甲基腺苷了解的很少，但新证据表明它是一种非常常见的碱基修饰和重要的生理调节因子。N6-甲基腺苷在整个大脑发育过程中都会显著增加，并会在终止密码子、microRNA结合位点和UTR附近富集，表明了其在基因表达调节中的基础性作用。N6-甲基腺苷在人和小鼠之间也高度保守。
免疫原
BSA偶联的N6-甲基腺苷。
應用
染色质免疫沉淀分析：A representative lot from an independent laboratory detected N6-methyladenosine in RNA containing N6-methyladenosine (Dominissini, D., et al. (2012).Nature.485(7397):201-206.; Meyer, K. D., et al. (2012).Cell.149(7):1635-1646.).
(RNA) Immunoprecipitation Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in methylated RNA containing N6-methyladenosine (Meyer, K. D., et al. (2012).Cell.149(7):1635-1646.).
Dot Blot Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in a panel of modified oligonucleotides (Meyer, K. D., et al. (2012).Cell.149(7):1635-1646.; Jia, G., et al. (2011).Nat Chem Biol. 7(12):885-887.).
(RNA) Immunoprecipitation Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in methylated RNA containing N6-methyladenosine (Meyer, K. D., et al. (2012).Cell.149(7):1635-1646.).
Dot Blot Analysis: A representative lot from an independent laboratory detected N6-methyladenosine in a panel of modified oligonucleotides (Meyer, K. D., et al. (2012).Cell.149(7):1635-1646.; Jia, G., et al. (2011).Nat Chem Biol. 7(12):885-887.).
研究子类别
染色质生物学
染色质生物学
研究类别
表观遗传学&核功能
表观遗传学&核功能
通过使用已验证用于斑点印迹、染色质IP（ChIP) & RNA结合蛋白IP（RIP）的抗-N6-甲基腺苷（m6A）抗体检测N6-甲基腺苷（m6A）。
品質
已通过斑点印迹在含有N6-甲基腺苷的低聚物中进行评估。
斑点印迹分析： 1 µg/mL的该抗体可在含有N6-甲基腺苷的低聚物中检测到N6-甲基腺苷。
斑点印迹分析： 1 µg/mL的该抗体可在含有N6-甲基腺苷的低聚物中检测到N6-甲基腺苷。
外觀
在含有0.05%叠氮化钠PBS的缓冲液中的纯化兔多抗。
形式：纯化
纯化的蛋白 A
儲存和穩定性
自发运之日起，在 2-8°C 条件下可稳定保存1年
其他說明
浓度：请参考批次特异性浓缩物的分析证书。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Andrea Orioli et al.
Genome research, 26(5), 624-635 (2016-03-05)
RNA polymerase III (Pol III) is tightly controlled in response to environmental cues, yet a genomic-scale picture of Pol III regulation and the role played by its repressor MAF1 is lacking. Here, we describe genome-wide studies in human fibroblasts that
Maximilian Anders et al.
Life science alliance, 1(4), e201800113-e201800113 (2018-11-21)
Reversible post-transcriptional modifications on messenger RNA emerge as prevalent phenomena in RNA metabolism. The most abundant among them is N6-methyladenosine (m6A) which is pivotal for RNA metabolism and function; its role in stress response remains elusive. We have discovered that
Xiao-Cui Li et al.
Theranostics, 9(13), 3853-3865 (2019-07-10)
N6-Methyladenosine (m6A) is the most prevalent internal modification in mammalian mRNAs. Although m6A is important in many biological processes, its roles in the placenta are unclear. Methods: Levels of global mRNA m6A methylation and ALKBH5 expression in recurrent miscarriage (RM)
Taylor M Nye et al.
PLoS pathogens, 15(6), e1007841-e1007841 (2019-06-18)
DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the contribution of m6A to the regulation of gene expression is unclear in many organisms. Here we
Hua Su et al.
BMC genomics, 21(1), 39-39 (2020-01-15)
Hypoxia mediated pulmonary hypertension (HPH) is a lethal disease and lacks effective therapy. CircRNAs play significant roles in physiological process. Recently, circRNAs are found to be m6A-modified. The abundance of circRNAs was influenced by m6A. Furthermore, the significance of m6A
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