8.51025

5-Carboxyfluorescein

Novabiochem^®

• 别名: 5-Carboxyfluorescein, 5-FAM
• 经验公式（希尔记法）: C₂₁H₁₂O₇
• CAS号: 76823-03-5
• 分子量: 376.32
• MDL编号: MFCD00036874
• UNSPSC代码: 12352005
• NACRES: NA.22

属性

• 质量水平: 200
• 产品线: Novabiochem^®
• 方案: ≥98% (TLC); ≥99.0% (HPLC)
• 表单: powder
• 反应适用性: reagent type: fluorescent-labelling reagent
• 制造商/商品名称: Novabiochem^®
• 应用: peptide synthesis
• 储存温度: 2-8°C
• SMILES字符串: O1C3(c4c(cc(cc4)O)Oc5c3ccc(c5)O)c2c(cc(cc2)C(=O)O)C1=O
• InChI: 1S/C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21/h1-9,22-23H,(H,24,25)
• InChI key: NJYVEMPWNAYQQN-UHFFFAOYSA-N

说明

一般描述

This high purity fluorescent dye (λ_ex494 nm, λ_em 518 nm) is supplied as a single isomer, which ensures production of labeled products of defined chemical structure, as well as greatly simplifying purification and characterization. FAM should be introduced as the last step in the synthesis to avoid formation of side-products, or be protected by tritylation prior to acylation or hydrazine treatment ^[1].

Associated Protocols and Technical Articles
Chromogenic Labeling of Synthetic Peptides

Literature references

^[1] R. Fischer, et al. (2003) Bioconjugate Chem., 14, 653.

应用

5-Carboxyfluorescein Novabiochem^®. CAS 76823-03-5, molar mass 376.32 g/mol.

联系

Replaces: 01-63-0112

分析说明

Colour (visual): yellow to orange
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC (EtOAc/MeOH/H2O/DIPEA 60 : 30 : 10 : 3)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable