580560

三(2-羰基乙基)磷盐酸盐

A water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT.

• 别名: 三(2-羰基乙基)磷盐酸盐
• 经验公式（希尔记法）: C₉H₁₅O₆P · xHCl
• CAS号: 51805-45-9
• 分子量: 250.19 (free base basis)
• MDL號碼: MFCD00145469
• 分類程式碼代碼: 12352128
• NACRES: NA.25

属性

• 品質等級: 100
• 化驗: ≥98% (elemental analysis)
• 形狀: crystalline solid
• 反應適用性: reagent type: reductant
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated
• 顏色: white
• 溶解度: water: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)/p-3
• InChI 密鑰: PZBFGYYEXUXCOF-UHFFFAOYSA-K

说明

一般說明

一种水溶性、无味的二硫化物还原剂，比DTT更稳定、更有效。在pH值为4.5时，TCEP甚至可以在5分钟内还原最稳定的水溶性烷基二硫化物。即使在pH值为1.5-8.5，TCEP也能起到还原剂的作用。与DTT相比，它更耐空气氧化。

應用

• Peptide and Protein Desulfurization with Diboron Reagents.: This study investigates the use of TCEP hydrochloride in peptide and protein desulfurization, demonstrating its effectiveness in facilitating diboron-mediated reactions. (Jing & Walczak, 2024).


• A Study on Thiol-Michael Addition to Semi-Synthetic Elastin-Hyaluronan Material for Electrospun Scaffolds.: TCEP hydrochloride is utilized to enhance the thiol-Michael addition reaction in the development of electrospun scaffolds, contributing to advanced biomaterials research. (Laezza et al., 2024).


• Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis.: This paper presents an optimized protocol for RNA isolation from bovine sperm, highlighting the role of TCEP hydrochloride in improving sperm head lysis efficiency. (Tiwari et al., 2024).


• Target Recognition-Triggered Peroxidase-Mimicking Activity Depression in Homochiral Nanochannels for Identifying Cystine Enantiomers.: The study uses TCEP hydrochloride in a novel peroxidase-mimicking system to differentiate cystine enantiomers, showcasing its application in chiral analysis. (Xu et al., 2023).


• In situ digestion of alcohol-fixed cells for quantitative proteomics.: TCEP hydrochloride is applied in the in situ digestion of fixed cells to enhance the accuracy of quantitative proteomics analyses. (Hatano et al., 2023).

包裝

用惰性气体包装

警告

毒性：腐蚀性（L）

其他說明

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法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H314
• 防範說明: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• 危險分類: Eye Dam. 1 - Skin Corr. 1B
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 1