推荐产品
生物源
synthetic (organic)
品質等級
產品線
BioUltra
化驗
≥99% (NMR)
形狀
powder
雜質
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
mp
92-95 °C (lit.)
溶解度
H2O: 0.5 M, clear, colorless
負離子痕跡
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
正離子痕跡
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
儲存溫度
2-8°C
SMILES 字串
NC(=O)CI
InChI
1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI 密鑰
PGLTVOMIXTUURA-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
應用
碘乙酰胺已用于：
- 蛋白质组学分析的蛋白质消化
- 烷基化蛋白质样品
- 牛奶过敏原、β-乳球蛋白（BLG）和α-乳清蛋白（ALA）的变性
生化／生理作用
碘乙酰胺（IAA）被用于抑制糖酵解，因为它能够不可逆地抑制糖酵解酶甘油醛-3-磷酸脱氢酶（GAPDH）。IAA用于研究半胱氨酸残基在酶催化和脑细胞转运过程中的作用。它可以与巯基乙醇和谷胱甘肽等低分子量硫醇化合物发生反应。IAN还可能阻断菠萝蛋白酶、组织蛋白酶C、梭状芽孢蛋白酶和羧肽酶P等酶。
碘乙酰胺在肽测序中胱氨酸残基的烷基化试剂。它是活性位点上含有胱氨酸的酶的的一种不可逆抑制剂。它与组氨酸残基的反应速度要慢得多，但这种活性是核糖核酸酶抑制的原因。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
其他客户在看
Tommy Weiss-Sadan et al.
Theranostics, 9(20), 5731-5738 (2019-09-20)
Despite the common use of lipid-lowering medications, cardiovascular diseases continue to be a significant health concern. Atherosclerosis, one of the most frequent causes of cardiovascular morbidity, involves extensive inflammatory activity and remodeling of the vascular endothelium. This relentless inflammatory condition
Konstantinos Boulias et al.
Molecular cell, 75(3), 631-643 (2019-07-08)
mRNAs are regulated by nucleotide modifications that influence their cellular fate. Two of the most abundant modified nucleotides are N6-methyladenosine (m6A), found within mRNAs, and N6,2'-O-dimethyladenosine (m6Am), which is found at the first transcribed nucleotide. Distinguishing these modifications in mapping
Mirko Zaffagnini et al.
Antioxidants & redox signaling, 16(1), 17-32 (2011-06-29)
Cysteines (Cys) made acidic by the protein environment are generally sensitive to pro-oxidant molecules. Glutathionylation is a post-translational modification that can occur by spontaneous reaction of reduced glutathione (GSH) with oxidized Cys as sulfenic acids (-SOH). The reverse reaction (deglutathionylation)
Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
Elena B Lugli et al.
Arthritis research & therapy, 17, 9-9 (2015-01-21)
Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门