跳转至内容
Merck
所有图片(1)

文件

572201

Millipore

链脲佐菌素

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

别名:

链脲佐菌素

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C8H15N3O7
CAS号:
分子量:
265.22
MDL號碼:
分類程式碼代碼:
12352103

品質等級

化驗

≥95% (HPLC)

形狀

crystalline solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

顏色

off-white to pale yellow

溶解度

water: soluble

正離子痕跡

heavy metals: ≤5 ppm

運輸包裝

ambient

儲存溫度

−20°C

InChI

1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1

InChI 密鑰

ZSJLQEPLLKMAKR-GKHCUFPYSA-N

相关类别

一般說明

含 N-亚硝基的促糖尿病化合物,在胰岛中充当一氧化氮供体。一种对革兰氏阴性细菌有效的抗生素。在胰腺胰岛细胞中引起 DNA 烷基化和 DNA 链断裂。
含 N-亚硝基的化合物,在胰岛中充当一氧化氮的供体。一种对革兰氏阴性细菌有效的抗生素。在胰腺胰岛细胞中引起 DNA 烷基化和 DNA 链断裂。致糖尿病剂。

警告

毒性:有害 & 致癌/致畸性(E)

重構

溶液中不稳定;仅在使用前进行重悬。初次融化后,等分并冷冻(-20°C)。

其他說明

Kroncke, K.D., et al. 1995.Biol. Chem. Hoppe Seyler376, 179.
Kwon, N.S., et al. 1994.FASEB J.8, 529.
Rasschaert, J., et al. 1992.Endocrinology130, 3522.
Bennett, R.A. and Pegg, A.E.1981.Cancer Res.41, 2786.
Adams, J., et al. 1981.Nature294, 284.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

FlameHealth hazard

訊號詞

Warning

危險聲明

危險分類

Carc. 2 - Flam. Sol. 2 - Muta. 2

儲存類別代碼

4.1B - Flammable solid hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Qin Jiang et al.
The Journal of clinical investigation, 130(7), 3833-3847 (2020-04-29)
Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults. Vascular pericyte degeneration is the predominant clinical manifestation of DR, yet the mechanism governing pericyte degeneration is poorly understood. Circular RNAs (circRNAs) play important roles in multiple biological
Dezhi Chen et al.
Molecular medicine reports, 23(2) (2020-12-15)
Diabetic cardiomyopathy (DCM) is one of the primary complications of the cardiovascular system due to diabetes‑induced metabolic injury. The present study investigated the autophagy‑associated regulatory mechanisms of long non‑coding RNAs in cardiac pathological changes in diabetes mellitus (DM). Streptozotocin (STZ)‑induced
Zhongkun Ren et al.
Molecular medicine reports, 21(6), 2475-2483 (2020-04-03)
Epigallocatechin-3-gallate (EGCG) is beneficial for inhibiting dyslipidemia and reducing hyperlipidemic risk. The purpose of the present study was to investigate the glycolipid regulatory effects and potential mechanisms of EGCG in a high‑fat diet and streptozotocin‑induced type 2 diabetes mellitus (T2DM) mouse model.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门