A potent competitive antagonist of nAChR (IC50= 41 nM). Used as nondepolarizing muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvant.
生化/生理作用
Primary Target nAch
警告
Toxicity: Toxic (F)
制备说明
Warming is required for complete solubilization.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Bowman, C., 2006. Br. J. Pharmacol.147, S277. Wenningmann, I., et al. 2001. Mol. Pharmacol.60, 790. Pederson, X., 1990. Proc. Natl. Acad. Sci. USA.87, 2785.
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法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany