345736

Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain

Useful as a differentiation marker of tumor cell growth.

• 别名: Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain, Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
• 经验公式（希尔记法）: C₈₄H₁₄₆N₄O₃₉ · 2NH₄
• 分子量: 1872.14
• UNSPSC代码: 12352211
• NACRES: NA.77

属性

• 质量水平: 100
• 方案: ≥98% (TLC)
• 表单: lyophilized
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze
• 溶解性: DMSO: soluble; chloroform/methanol (2:1): soluble
• 运输: ambient
• 储存温度: −20°C

说明

一般描述

Disialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.



Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.

Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.

生化/生理作用

Cell permeable: no

Primary Target
Protein kinase C

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

制备说明

For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.

重悬

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

其他说明

Longee, D.C., et al. 1991. Acta Neuropathologica82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato.232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem.50, 733.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable