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Merck
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219426

Sigma-Aldrich

Cathepsin L Inhibitor II

The Cathepsin L Inhibitor II controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

别名:

Z-FY-CHO

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

顏色

off-white

溶解度

ethanol: 50 mg/mL
DMSO: soluble

運輸包裝

ambient

儲存溫度

−20°C

一般說明

A potent and selective inhibitor of Cathepsin L (Cat. No. 219402).

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

Z-Phe-Tyr-CHO

其他說明

Woo, J.-T., et al. 1996. Eur. J. Pharmacol. 300, 131.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Stephan Quintin et al.
The Journal of biological chemistry, 299(7), 104912-104912 (2023-06-13)
α-synuclein (αS) is an abundant, neuronal protein that assembles into fibrillar pathological inclusions in a spectrum of neurodegenerative diseases that include Lewy body diseases (LBD) and Multiple System Atrophy (MSA). The cellular and regional distributions of pathological inclusions vary widely
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microPublication biology, 2022 (2023-01-07)
Several studies have indicated a role for cathepsin L (CTSL) proteolytic activity in the nucleus under distinct cellular conditions, including during differentiation, senescence, and quiescence. Here we show that addition of CTSL inhibitors to a cell lysis buffer prevents the

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