1.00886

4-羟基苯甲酸乙酯钠盐

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• 别名: Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt
• 经验公式（希尔记法）: C₉H₉NaO₃
• CAS号: 35285-68-8
• 分子量: 188.16
• MDL编号: MFCD00016475
• UNSPSC代码: 12352108
• EC索引号: 252-487-6

属性

• Agency: BP; NF; Ph. Eur.
• 质量水平: 500
• 产品线: EMPROVE^® ESSENTIAL
• 表单: solid
• pH值（酸碱度）: 10 (20 °C, 1 g/L in H₂O)
• 沸点: 297 °C/1013 hPa (free ester,decomposition)
• mp: >115 °C (free ester)
• 转变温度: flash point 121 °C
• 溶解性: 1000 g/L
• 应用: liquid formulation; ophthalmics; pharmaceutical
• 储存温度: 15-25°C
• SMILES字符串: [Na+].[O-]c1ccc(cc1)C(=O)OCC
• InChI: 1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1
• InChI key: QYNMSPKSYXPZHG-UHFFFAOYSA-M

说明

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS05
• 警示用语：: Danger
• 危险声明: H318
• 预防措施声明: P280 - P305 + P351 + P338
• 危险分类: Eye Dam. 1
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): 249.8 °F
• 闪点(°C): 121 °C