1.00164

硼酸

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• 别名: Orthoboric acid, Trihydroxidoboron
• 线性分子式: H₃BO₃
• CAS号: 10043-35-3
• 分子量: 61.83
• MDL编号: MFCD00011337
• UNSPSC代码: 12352106
• EC索引号: 233-139-2

属性

• Agency: BP; NF; Ph. Eur.
• 质量水平: 600
• 蒸汽压: 2.6 mmHg ( 20 °C)
• 产品线: EMPROVE^® API
• 方案: 99.5-100.5% (alkalimetric)
• 表单: solid
• 效能: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH值（酸碱度）: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• 溶解性: 49.2 g/L
• 密度: 1.489 g/cm³ at 23 °C
• 堆积密度: 400‑600 kg/m³
• 痕量阴离子: sulfate (SO₄^2-): ≤0.04%
• 痕量阳离子: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• 应用: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• 储存温度: 2-25°C
• SMILES字符串: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

说明

一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS08
• 警示用语：: Danger
• 危险声明: H360FD
• 预防措施声明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危险分类: Repr. 1B
• 储存分类代码: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable