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Merck
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文件

09-101

Sigma-Aldrich

Anti-cGMP (cyclic GMP) Antibody

serum, Upstate®

别名:

Guanosine 3′, 5′-cyclic monophosphate

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

100

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性（以同源性預測）

all

製造商／商標名

Upstate®

技術

ELISA: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable

同型

IgG

NCBI登錄號

NM_001098512.1
NM_006258.2

UniProt登錄號

Q13976

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... PRKG1(5592)

特異性

Recognizes cGMP. Very little cross reactivity to cAMP based on ELISA.

免疫原

2 Monosuccinyl cyclic GMP conjugated to KLH

應用

Anti-cGMP (cyclic GMP) Antibody detects level of cGMP (cyclic GMP) & has been published & validated for use in ELISA, IH, RIA.
Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

品質

Routinely evaluated by ELISA

外觀

Serum

儲存和穩定性

2 years at -20°C from date of shipment

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

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Chongyang Zhang et al.
Journal of the American Heart Association, 11(2), e023053-e023053 (2022-01-06)
Background cGMP-hydrolyzing phosphodiesterase type 5 (PDE5) regulates vascular smooth muscle cell (SMC) contraction by antagonizing cGMP-dependent protein kinase I (PKGI)-dependent SMC relaxation. SMC contractile dysfunction is implicated in the pathogenesis of aortic aneurysm. PDE5 inhibitors have been used for treating
Susanne Vogeler et al.
BMC developmental biology, 20(1), 23-23 (2020-11-25)
Nitric oxide (NO) is presumed to be a regulator of metamorphosis in many invertebrate species, and although NO pathways have been comparatively well-investigated in gastropods, annelids and crustaceans, there has been very limited research on the effects of NO on

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