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Merck

857136C

Avanti

18:1 BMP (R,R)

sn-(1-oleoyl-2-hydroxy)-glycerol-3-phospho-sn-3′-(1′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), chloroform

别名:

bis(monoacyl-glycerol)phosphate, lysobisphosphatidic acid; LBPA

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About This Item

经验公式(希尔记法):
C42H82NO10P
分子量:
792.07
UNSPSC代码:
12352211

方案

>99% (BMP (contains 30% positional isomers), TLC)

表单

chloroform solution

包装

pkg of 1 × 1 mL (857136C-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 857136C

浓度

5 mg/mL (857136C-5mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP(OC[C@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

一般描述

18:1 BMP (R,R)/Lysobisphosphatidic acid (LBPA) is an unconventional phospholipid. It is usually present in late endosomes.[1] It is also termed as bis(monoacyl-glycerol)phosphate.[2][1]

生化/生理作用

18:1 BMP (R,R)/Lysobisphosphatidic acid (LBPA) can modulate endosomal cholesterol levels. It participates in cholesterol transport. LBPA helps to regulate the cholesterol storage capacity of endosomes.[1]

包装

5 mL Clear Glass Sealed Ampule (857136C-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The stereochemical configuration of lysobisphosphatidic acid from rat liver, rabbit lung and pig lung
Joutti A, et al.
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 450(2), 206-209 (1976)
Lysobisphosphatidic acid controls endosomal cholesterol levels
Chevallier J, et al.
The Journal of Biological Chemistry, 283(41), 27871-27880 (2008)
Elena Zaitseva et al.
PLoS pathogens, 6(10), e1001131-e1001131 (2010-10-16)
Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that infects up to 100 million people each

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