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Merck

830845P

Avanti

14:0 PA

1,2-dimyristoyl-sn-glycero-3-phosphate (sodium salt), powder

别名:

1,2-二十四烷酰基-sn-甘油-3-磷酸(钠盐);DMPA;PA(14:0/14:0)

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About This Item

经验公式(希尔记法):
C31H60O8PNa
CAS号:
分子量:
614.77
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 200 mg (830845P-200mg)
pkg of 1 × 25 mg (830845P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 830845P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C31H61O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(32)37-27-29(28-38-40(34,35)36)39-31(33)26-24-22-20-18-16-14-12-10-8-6-4-2;/h29H,3-28H2,1-2H3,(H2,34,35,36);/q;+1/p-1/t29-;/m1./s1

InChI 密鑰

UBSPGYHFNIKQIP-XXIQNXCHSA-M

一般說明

磷脂酸是在磷脂酶D的帮助下从甘油磷脂获得的。14:0 PA/a带负电荷的1,2-二肉豆蔻酰基-sn-甘油-3-磷酸酯(DMPA)带有磷酸头基。

應用

14:0 PA可用于制备脂质体。它也可以用作磷脂(PL)标准品,以定量磷脂酸(PA)。

生化/生理作用

磷脂酸可用作吞噬细胞呼吸爆发的调节剂。它也是二酰基甘油和溶血磷脂酸的前体。

包裝

5 mL棕色玻璃螺旋盖小瓶(830845P-200mg)
5 mL棕色玻璃螺旋盖小瓶(830845P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Although a minor component of the lipidome, phosphatidic acid (PA) plays a crucial role in nearly all signaling pathways involving cell membranes, in part because of its variable electrical charge in response to environmental conditions. To investigate how charge is
Glycerolipids in signal transduction
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The Journal of biological chemistry, 295(10), 2932-2947 (2020-01-26)
The δ isozyme of diacylglycerol kinase (DGKδ) plays critical roles in lipid signaling by converting diacylglycerol (DG) to phosphatidic acid (PA). We previously demonstrated that DGKδ preferably phosphorylates palmitic acid (16:0)- and/or palmitoleic acid (16:1)-containing DG molecular species, but not

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