推荐产品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (791643C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
1 mg/mL (791643C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
18:1-d7 Lyso PC 1油酰基(d7)-2-羟基-sn-甘油-3-磷酸胆碱是氘代磷脂。该脂质溶血磷脂酰胆碱是以油酸酯化。油酸包含氘离子。溶血磷脂酰胆碱（LPC） 是在磷脂酶 A2 的作用下由磷脂酰胆碱衍生而来。
这种氘标记的脂质也可用于多种脂质标准品制剂中。SPLASH™ LIPIDOMIX™ 标准品包括与人血浆的所有主要脂质类别对应的脂质，从而实现一种简单的内标溶液适用每种样品。
應用
18:1-d7 Lyso PC 已用于:
- 作为高效液相色谱电喷雾电离串联质谱（HPLC-ESIMS/MS） 的内标物，用于来源于骨髓的巨噬细胞的脂质组学分析
- 作为提取溶剂的成分，用于从生物样品中分离脂质
- 作为液相色谱串联质谱（LC-MS/MS）中血清样品的内标物
生化／生理作用
溶血磷脂酰胆碱（LPC）。LPC 水平升高与糖尿病和心血管疾病有关。LPC 刺激细胞因子并与过敏性疾病有关。它还导致膜上的裂解。
包裝
5 mL透明玻璃密封安瓿（791643C-1mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
其他客户在看
Preeti Bansal et al.
Scientific reports, 6, 27430-27430 (2016-06-11)
Phospholipase A2 (sPLA2), pivotal for allergic and inflammatory response, hydrolyses phosphatidylcholine (PC) to lysophosphatidylcholine (LPC). In present study, the role of LPC in allergic airway disease manifestation was studied using mouse model. Balb/c mice were immunized using cockroach extract (CE)
Shi-Hui Law et al.
International journal of molecular sciences, 20(5) (2019-03-09)
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively associated with cardiovascular and neurodegenerative diseases. However, findings from recent clinical lipidomic studies of LPC have been controversial. A key issue is the complexity of the enzymatic cascade involved in
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
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