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质量水平
表单
powder
粒径
5 μm
孔径
non-porous
沸点
2230 °C (lit.)
mp
>1600 °C (lit.)
SMILES字符串
O=[Si]=O
InChI
1S/O2Si/c1-3-2
InChI key
VYPSYNLAJGMNEJ-UHFFFAOYSA-N
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一般描述
Our monodisperse, non-porous silica powder is a white powder composed of speherical particles, precisely engineered to achieve a monodisperse particle size of 5 µm with 99.99% purity. The microparticles do not contain any internal porosity or void spaces, making their surfaces impermeable to fluids or gases.
应用
Monodisperse, non-porous silica particles have several applications in various research areas including drug delivery, molecular imaging, and environmental remediation. Owing to their stable chemical structure, ease of surface modification, and affinity toward various biomolecules, silica microparticles are an attractive platform for bioconjugation of drugs, proteins, DNA, and other biomarkers. Consequently, non-porous silica particles and their bioconjugates are used in biomedical applications for delivering or isolating drugs, proteins, polynucleotides, and more. Bioconjugation of non-porous silica often facilitates imaging techniques including optical imaging (fluorescence and bioluminescence), magnetic resonance imaging (MRI), radionuclide imaging, computed tomography (CT), ultrasound, photoacoustic imaging, and Raman imaging.[1],[2]Apart from these applications, these monodisperse particles are also used in analytical applications, such as the stationary phase in columns for advanced, high-performance liquid chromatography.[3]
储存分类代码
11 - Combustible Solids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Nonporous Silica Nanoparticles for Nanomedicine Application
Tang L, et al.
Nano Today, 8, 290-312 (2013)
Safety of Nonporous Silica Nanoparticles in Human Corneal Endothelial Cells
Kim J Y, et al
Scientific Reports, 7, 14566-14566 (2017)
Nano-Bio Interactions of Porous and Nonporous Silica Nanoparticles of Varied Surface Chemistry: A Structural, Kinetic, and Thermodynamic Study of Protein Adsorption from RPMI Culture Medium
Lehman S, et al.
Langmuir, 32, 731-742 (2016)
Core-shell particles lead the way to renewing high-performance liquid chromatography
Gonzalez-Ruiz V, et al
TrAC, Trends in Analytical Chemistry, 64, 17-28 (2015)
Sean E Lehman et al.
Langmuir : the ACS journal of surfaces and colloids, 32(3), 731-742 (2015-12-31)
Understanding complex chemical changes that take place at nano-bio interfaces is of great concern for being able to sustainably implement nanomaterials in key applications such as drug delivery, imaging, and environmental remediation. Typical in vitro assays use cell viability as
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