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730971

Sigma-Aldrich

2-（二异丙基氨基）甲基丙烯酸乙酯

97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor

别名:

DPA, DPAEMA

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25 G
$158.00
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About This Item

经验公式（希尔记法）:
C12H23NO2
CAS号:
16715-83-6
分子量:
213.32
EC 号:
240-772-8
MDL编号:
MFCD00072647
UNSPSC代码:
12162002
PubChem化学物质编号:
329764609
NACRES:
NA.23

$158.00

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质量水平

100

方案

97%

表单

liquid

包含

~100 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.145

密度

0.900 g/mL at 25 °C

储存温度

2-8°C

SMILES字符串

CC(C)N(CCOC(=O)C(C)=C)C(C)C

InChI

1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3

InChI key

SVYHMICYJHWXIN-UHFFFAOYSA-N

相关类别

一般描述

2-(二异丙基氨基)甲基丙烯酸乙酯(DPA)是一种甲基丙烯酸类单体，用于制备各种DPA聚合物，包括聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDPA)。PDPA是水溶性聚合物，对pH和温度变化敏感。在低于pKa值（约6.5）的pH下，PDPA会由疏水变为亲水。这种转变是因为它的氨基发生质子化。PDPA聚合物这一独特性质令其十分适合药物递送、基因递送、传感器、表面、膜和色谱等各种各样的应用。[1][2]

应用

2-(二异丙基氨基)甲基丙烯酸乙酯可用于：
  • 作为单体，用于聚寡乙二醇甲基丙烯酸甲酯(P(OEGMA))和聚2-(二异丙基氨基)甲基丙烯酸乙酯(PDIPAEMA)经RAFT聚合反应合成多重响应性超支化共聚物。获得的聚合物可用于药物递送、基因递送和组织工程。
  • 作为单体合成嵌段共聚物聚乙二醇-b-聚2-(二异丙基氨基)甲基丙烯酸乙酯(PEG-b-PDPAEMA)。这类pH响应型胶束可用于改进细胞内药物递送。DPA单体负责共聚物的pH响应性。

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

210.0 °F

闪点(°C)

98.9 °C

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW8001
MKCV2458
MKCS9208
MKCT6248
MKCR8203

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Robert K McNamara et al.
Prostaglandins, leukotrienes, and essential fatty acids, 136, 23-34 (2017-05-23)
There is a substantial body of evidence from animal studies implicating polyunsaturated fatty acids (PUFA) in neuroinflammatory, neurotrophic, and neuroprotective processes in brain. However, direct evidence for a role of PUFA in human brain structure and function has been lacking.
Emma von Wowern et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 30(19), 2309-2314 (2016-10-14)
Uterine artery (UtA) Doppler velocimetry changes and increased arterial stiffness are associated with preeclampsia. We aimed to investigate the relation between UtA velocimetry changes and arterial stiffness in pregnant women. Doppler velocimetry and photoplethysmographic digital pulse wave analysis (DPA) were
Daniel Martínez-Laguna et al.
PloS one, 13(9), e0203533-e0203533 (2018-09-08)
An increased fracture risk has been described as a complication of Type 2 diabetes mellitus (T2DM). Clinical prediction models for general population have a limited predictive accuracy for fractures in T2DM patients. The aim was to develop and validate a
Laurent Maïmoun et al.
Clinical physiology and functional imaging, 39(5), 345-354 (2019-05-16)
Dual-energy X-ray absorptiometry (DXA) is used in clinical routine to determine areal bone mineral density (aBMD). However, it is not clear whether excessive fat mass or substantial weight loss modify the aBMD measurements. The aim of this study was to
Fernando H Ramírez-Guadiana et al.
PLoS genetics, 13(9), e1007015-e1007015 (2017-09-26)
One of the hallmarks of bacterial endospore formation is the accumulation of high concentrations of pyridine-2,6-dicarboxylic acid (dipicolinic acid or DPA) in the developing spore. This small molecule comprises 5-15% of the dry weight of dormant spores and plays a
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