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Merck

676713

Sigma-Aldrich

1,2-二溴-3-氯丙烷

97%

别名:

DBCP

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5 G
$91.60
25 G
$167.00

About This Item

线性分子式:
CH2BrCHBrCH2Cl
CAS号:
分子量:
236.33
Beilstein:
1732077
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

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方案

97%

折射率

n/D 1.5542

沸点

60-65 °C/7.5 mmHg

密度

2.081 g/mL at 25 °C

官能团

bromo
chloro

SMILES字符串

ClCC(Br)CBr

InChI

1S/C3H5Br2Cl/c4-1-3(5)2-6/h3H,1-2H2

InChI key

WBEJYOJJBDISQU-UHFFFAOYSA-N

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应用

1,2-Dibromo-3-chloropropane can be used to prepare:
  • Tritium radiolabeled dibromochloropropane.[1]
  • L-Glutathione conjugates, which are used to alkylate the DNA to yield N7-guanyl adducts.[2]

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B - Muta. 1B - Repr. 1A - STOT RE 2 Oral

靶器官

Testes

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

170.1 °F

闪点(°C)

76.7 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Isolation and characterization of N7-guanyl adducts derived from 1, 2-dibromo-3-chloropropane
Humphreys WG, et al.
Chemical Research in Toxicology, 4(4), 445-453 (1991)
An improved synthesis of labelled dibromochloropropane
Buchman O, et al.
Journal of Labelled Compounds & Radiopharmaceuticals, 18(12), 1713-1719 (1981)
1,2-Dibromo-3-chloropropane.
Report on carcinogens : carcinogen profiles, 12, 134-135 (2011-08-20)
Daniel Albert et al.
Arthritis and rheumatism, 51(4), 656-664 (2004-08-31)
To investigate the possibility that environmental agents contribute to the pathogenesis of Wegener's granulomatosis (WG). We undertook an extensive search for possible environmental exposures by developing a comprehensive questionnaire that was administered by telephone interview to 53 patients with WG
Juraj Lábaj et al.
Nutrition and cancer, 57(2), 209-215 (2007-06-19)
The aim of our investigation was to verify the protective effect of lignin on DNA in rat hepatocytes damaged by 3 different genotoxins attacking DNA in a different manner. Hydrogen peroxide was used for induction of direct single strand breaks

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