It is an encapsulated catalyst (EnCat®), wherein palladium acetate and triphenylphosphine(TPP)are microencapsulated within a polyurea matrix, which prevents palladium leaching.
Pd EnCat® TPP30 may be used as a catalyst for the microwave-assisted Sonogashira cross-coupling of:
Aryl iodides and bromides with terminal alkynes to form the corresponding coupling products under copper-free conditions.[4]
Bromobenzotriazoles and arylacetylenes in the presence of 1,5-diazabicyclo[5.4.0]undecene-5-ene (DBU) and copper iodide to form 2H-benzo[d][1,2,3]triazole derivatives.[5]
特点和优势
The advantages of using Pd EnCat® catalysts are:
low residual metal levels in crude product
easy recovery of catalyst
compatibility of immobilized metal with various ligands to effect C-C bond forming reactions
safer and easier to handle than Pd/C for hydrogenation
efficiency and economy gains through recovery and recycling
Self-assembly of T-shape 2H-benzo[d][1,2,3]-triazoles. Optical waveguide and photophysical properties.
Torres I, et al.
Royal Society of Chemistry Advances, 6(43), 36544-36553 (2016)
Pd-EnCatTM TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl-and Alkenyl-Substituted Acetylenes via Microwave-Assisted Sonogashira Type Reactions.
Sedelmeier J, et al.
European Journal of Organic Chemistry, 2009(26), 4412-4420 (2009)
Chemical communications (Cambridge, England), (10), 1134-1135 (2002-07-19)
Palladium(II) acetate microencapsulated in polyurea (MC-[Pd]) is an economical and versatile heterogeneous catalyst for a range of phosphine-free cross-coupling reactions in both conventional solvents and supercritical carbon dioxide (scCO2); the catalyst can be recovered by a simple filtration and recycled
[reaction: see text] Pd nanoparticles (approximately 2 nm in size) microencapsulated in polyurea is an efficient and recyclable catalyst for reductive ring-opening hydrogenolysis of epoxides, using either HCOOH/Et(3)N or H(2) as a hydrogen donor.
Yu, J.Q., et al.
Chemical Communications (Cambridge, England), 678-697 (2003)
We offer EnCat and a variety of transition metal-based encapsulated catalysts for applications in areas such as Suzuki, Stille, and Heck couplings, carbonylations, hydrogenation, hydrogenolysis, and dihydroxylation.
