565849

4-(三氟甲基)苯磺酰氯

97%

• 别名: α,α,α-Trifluoro-p-toluenesulfonyl chloride, 4-(Trifluoromethyl)benzene-1-sulfonyl chloride, [4-(Trifluoromethyl)phenyl]sulfonyl chloride, [p-(Trifluoromethyl)phenyl]sulfonyl chloride, p-Trifluoromethylbenzenesulfonyl chloride
• 线性分子式: CF₃C₆H₄SO₂Cl
• CAS号: 2991-42-6
• 分子量: 244.62
• Beilstein: 2113604
• MDL编号: MFCD00042422
• UNSPSC代码: 12352100
• PubChem化学物质编号: 24880261
• NACRES: NA.22

属性

• 质量水平: 100
• 方案: 97%
• mp: 30-34 °C (lit.)
• 官能团: fluoro
• SMILES字符串: FC(F)(F)c1ccc(cc1)S(Cl)(=O)=O
• InChI: 1S/C7H4ClF3O2S/c8-14(12,13)6-3-1-5(2-4-6)7(9,10)11/h1-4H
• InChI key: OZDCZHDOIBUGAJ-UHFFFAOYSA-N

说明

应用

4-(Trifluoromethyl)benzenesulfonyl chloride may be used to synthesize β-arylated thiophenes[1] and 2,5-diarylated pyrrole[2]via palladium catalyzed desulfitative arylation of thiophenes and pyrroles, respectively.[1][2]
4-(Trifluoromethyl)benzenesulfonyl chloride and N-vinylpyrrolidinone in acetonitrile can undergo photo-irradiation with visible light in the presence of Ir(ppy)₂(dtbbpy)PF₆ ([4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis[2-(2-pyridinyl-N)phenyl-C]iridium(III)hexafluorophosphate) and disodium phosphate to give the corresponding E-vinyl sulfone.[3]

注意

低熔点固体

安全信息

• 象形图: GHS05
• 警示用语：: Danger
• 危险声明: H314
• 预防措施声明: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• 危险分类: Skin Corr. 1B
• 补充剂危害: EUH014
• 储存分类代码: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 闪点(°F): >230.0 °F
• 闪点(°C): > 110 °C
• 个人防护装备: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter