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product name
Fmoc-L-天冬氨酸4-叔丁酯, ≥98.0% (HPLC)
化驗
≥98.0% (HPLC)
形狀
powder
光學活性
[α]20/D −24±2°, c = 1% in DMF
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
mp
148-150 °C (dec.)
應用
peptide synthesis
官能基
Fmoc
儲存溫度
2-8°C
SMILES 字串
CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
InChI 密鑰
FODJWPHPWBKDON-IBGZPJMESA-N
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一般說明
Fmoc-Asp(OtBu)-OH又称为Fmoc-L-天冬氨酸4-叔丁酯,在固相多肽合成中用作Fmoc-氨基酸类保护基团。
應用
Fmoc-Asp(OtBu)-OH可用于在Fmoc肽固相合成中防止天冬氨酰亚胺副产物的形成。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
New t-butyl based aspartate protecting groups preventing aspartimide formation in Fmoc SPPS
Journal of Peptide Science, 21, 680-687 (2015)
ACS applied materials & interfaces, 8(44), 29906-29914 (2016-10-21)
In this work, we reported the generation of a novel supramolecular hydrogelator from a peptide derivative which consisted of a structural motif (e.g., Fc-FF) for supramolecular self-assembly and a functional moiety (e.g., RGD) for integrin binding. Following self-assembly in water
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
Photodynamic therapy (PDT) is an established therapeutic modality for the management of cancers. Conjugation with tumor-specific small molecule ligands (e.g., short peptides or peptidomimetics) could increase the tumor targeting of PDT agents, which is very important for improving the outcome
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
相关内容
With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.
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