跳转至内容
Merck

42085

Sigma-Aldrich

2,4-二硝基氟苯

purum p.a., ≥98.0% (GC)

别名:

2,4-二硝基-1-氟苯, DNFB, DNPF, FDNB, 桑格试剂

登录查看公司和协议定价

选择尺寸

50 G
$220.00
250 G
$626.00

$220.00


国内现货,预计发货时间2025年4月08日详情


获取大包装报价

选择尺寸

变更视图
50 G
$220.00
250 G
$626.00

About This Item

线性分子式:
(O2N)2C6H3F
CAS号:
分子量:
186.10
Beilstein:
398632
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$220.00


国内现货,预计发货时间2025年4月08日详情


获取大包装报价

等级

purum p.a.

方案

≥98.0% (GC)

表单

liquid

折射率

n20/D 1.569 (lit.)

沸点

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

密度

1.482 g/mL at 25 °C (lit.)

痕量阳离子

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤100 mg/kg
Na: ≤100 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

官能团

fluoro
nitro

储存温度

2-8°C

SMILES字符串

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

1-氟-2,4-二硝基苯(FDNB,Sanger 试剂)用于鉴定氨基酸序列。这种化学物质用于标记蛋白质和多肽中的游离氨基。它也可用于保护胺基,并用于苯酚脱氧。此外,它在亲核取代反应中是一种非常有用的试剂,可引入胺、酚和硫醇的发色团。

应用

1-氟-2,4-二硝基苯用作衍生化剂:
  • 氨基糖苷类化合物,如阿米卡辛、妥布霉素、庆大霉素、西西霉素、奈胺、新霉素 B 和新霉素 C。
1-氟-2,4-二硝基苯也可用于:
  • 研究在几种表面活性剂存在下与硫醇反应的动力学分析和分析用途。

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

327.2 °F

闪点(°C)

164 °C

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

F Wang et al.
Journal of chromatography. A, 883(1-2), 113-118 (2000-07-26)
A rapid and simple method is presented for determining neuro-excitatory nonprotein amino acid 3-N-oxalyl-2,3-diaminopropionic acid (beta-ODAP) and non-protein amino acids in Lathyrus sativus. Seed and foliage extracts of Lathyrus sativus were treated with 1-fluoro-2,4-dinitrobenzene (FDNB) and a reversed-phase high-performance liquid
G Paraskevas et al.
Journal of pharmaceutical and biomedical analysis, 29(5), 865-872 (2002-07-03)
A spectrophotometric method for the determination of lisinopril (LN) in single and multicomponent tablets also containing hydrochlorothiazide (HCT), based on the derivatization reaction with 1-fluoro-2,4-dinitrobenzene (FDNB, Sanger reagent) is described. Aqueous solutions of LN (4.5-27.2 x 10(-5) M) react with
Helena Shifrin et al.
PloS one, 8(2), e57668-e57668 (2013-03-08)
The cholinergic anti-inflammatory system and α7 nicotinic receptors in macrophages have been proposed to play a role in neuroimmunomodulation and in the etiology of ulcerative colitis. We investigated the ability of a cholinesterase (ChE) inhibitor rivastigmine, to improve the pathology
Sonia Schuepbach-Mallepell et al.
The Journal of allergy and clinical immunology, 132(6), 1348-1357 (2013-08-21)
Innate immune sensors control key cytokines that regulate T-cell priming and T-cell fate. This is particularly evident in allergic reactions, which represent ideal systems to study the interplay of innate and adaptive immunity. In patients with contact dermatitis, inflammasome-mediated IL-1
Morten M Nielsen et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 2975-2983 (2014-03-07)
Substances that penetrate the skin surface can act as allergens and induce a T cell-mediated inflammatory skin disease called contact hypersensitivity (CHS). IL-17 is a key cytokine in CHS and was originally thought to be produced solely by CD4(+) T

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门