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Merck

393622

Sigma-Aldrich

对甲基苯硼酸

97%

别名:

4-甲基苯基硼酸, 4-甲苯硼酸, NSC 62870

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About This Item

线性分子式:
CH3C6H4B(OH)2
CAS号:
分子量:
135.96
Beilstein:
2935970
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22

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品質等級

化驗

97%

mp

256-263 °C (lit.)

SMILES 字串

Cc1ccc(cc1)B(O)O

InChI

1S/C7H9BO2/c1-6-2-4-7(5-3-6)8(9)10/h2-5,9-10H,1H3

InChI 密鑰

BIWQNIMLAISTBV-UHFFFAOYSA-N

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應用

试剂用于
  • 钯 (Pd) 催化的直接芳基化[1]
  • 直接钯 (II) 催化合成[2]
  • 水中 Suzuki-Miyaura 交叉偶联的钯催化芳基化[3]
  • 环钯化反应[4]
  • 串联型钯 (II) 催化的氧化 Heck 反应和分子内 C-H 酰胺化反应[5]
  • 钌催化直接芳基化[6]
  • 铑催化不对称共轭加成[7]
  • 无配体铜催化的交叉偶联反应[8]
  • Suzuki-Miyaura 和 Sonogashira 交叉偶联反应的区域选择性芳基化和炔基化[9]
  • 无配体 Suzuki、Sonogashira 和 Heck 交叉偶联反应[10]

制备过程中使用的试剂
  • 溴代芳烃的 Suzuki-Miyaura 交叉偶联反应的催化剂[4]
  • 通过点击离子共聚物固定的,用于 Suzuki-Miyaura 在水中的交叉偶联反应的可再循环的钯纳米颗粒催化剂[11]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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ACS Symp. Ser., 642, 194-205 (1996)
Palladium nanoparticles immobilized by click ionic copolymers: Efficient and recyclable catalysts for Suzuki-Miyaura cross-coupling reaction in water
Zhang, D.; Zhou, C.; Wang, R.
Catalysis Communications, 22, 83-88 (2012)
Daniel P O'Connell et al.
Bioorganic & medicinal chemistry letters, 22(3), 1397-1401 (2012-01-10)
Endothelial lipase (EL) and lipoprotein lipase (LPL) are homologous lipases that act on plasma lipoproteins. EL is predominantly a phospholipase and appears to be a key regulator of plasma HDL-C. LPL is mainly a triglyceride lipase regulating (V)LDL levels. The
Carbon-Carbon Bond Formation by Ligand-free Cross-Coupling Reaction Using Palladium Catalyst Supported on Synthetic Adsorbent
Monguchi, Y.; et al.
ChemCatChem, 4, 546-558 (2012)
Jiajia Tan et al.
Biomaterials, 178, 608-619 (2018-04-02)
Inflammation serves as a natural defense mechanism to protect living organisms from infectious diseases. Nonsteroidal anti-inflammatory drugs (NSAIDs) can help relieve inflammatory reactions and are clinically used to treat pain, fever, and inflammation, whereas long-term use of NSAIDs may lead

商品

MIDA-protected boronate esters offer stability, chromatography compatibility, and reactivity in anhydrous cross-coupling conditions.

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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