38827

4,4′-二甲氧基三苯甲基氯

≥97.0% (HPLC)

• 别名: 4,4′-二甲氧基氯化三苯甲烷, DMT, DMT-Cl, 氯-4,4′-二甲氧基三苯基甲烷
• 经验公式（希尔记法）: C₂₁H₁₉ClO₂
• CAS号: 40615-36-9
• 分子量: 338.83
• Beilstein: 2471942
• EC 号: 255-002-6
• MDL编号: MFCD00008409
• UNSPSC代码: 12352101
• PubChem化学物质编号: 57649867
• NACRES: NA.22

属性

• 方案: ≥97.0% (HPLC)
• mp: 123-125 °C
• 官能团: chloro; phenyl
• SMILES字符串: COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
• InChI: 1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
• InChI key: JBWYRBLDOOOJEU-UHFFFAOYSA-N
• 基因信息: human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358) ; rat ... Htr1a(24473) , Htr2a(29595)

说明

应用

4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:

• For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.[1][2]
• For 1⁰ sulfhydryl group of oligonucleotide analogs as its DMTr thioether.[3]

其他说明

有用的保护基团试剂[4][5][6]；移除[7]

安全信息

• 象形图: GHS05,GHS07,GHS09
• 警示用语：: Danger
• 危险声明: H314,H317,H335,H411
• 预防措施声明: P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危险分类: Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• 靶器官: Respiratory system
• 储存分类代码: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 3
• 个人防护装备: Eyeshields, Gloves, type N95 (US)