362433

N-甲氧基-N-甲羰基甲基膦酸二乙酯

96%

• 别名: N-Methoxy-N-methyl-phosphonoacetamide diethyl ester, Diethyl N-methoxy-N-methylphosphonoacetamide
• 线性分子式: CH₃ON(CH₃)COCH₂P(O)(OC₂H₅)₂
• CAS号: 124931-12-0
• 分子量: 239.21
• Beilstein: 1875865
• MDL號碼: MFCD00134233
• 分類程式碼代碼: 12352108
• PubChem物質ID: 24862312
• NACRES: NA.22

属性

• 化驗: 96%
• 形狀: liquid
• 反應適用性: reaction type: C-C Bond Formation
• 折射率: n20/D 1.455 (lit.)
• bp: 90 °C/17 mmHg (lit.)
• 密度: 1.163 g/mL at 25 °C (lit.)
• 官能基: amine; phosphonate
• SMILES 字串: CCOP(=O)(CC(=O)N(C)OC)OCC
• InChI: 1S/C8H18NO5P/c1-5-13-15(11,14-6-2)7-8(10)9(3)12-4/h5-7H2,1-4H3
• InChI 密鑰: WYLRYBDGIILFIR-UHFFFAOYSA-N

说明

應用

Reactant for:

• Preparation of ring-expanded bryostatin analogs as antitumor agents
• Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization
• Rh2(II)-catalyzed nitro-group migration reactions
• Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions
• Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps
• Preparation of substituted furans via olefin cross-metathesis

Wittig 羰基化试剂

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 230.0 °F - closed cup
• 閃點（°C）: 110 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter