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Merck

346152

Sigma-Aldrich

乙炔基溴化镁 溶液

0.5 M in THF

别名:

乙炔基溴化镁, 乙炔溴化镁, 溴乙炔镁

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About This Item

线性分子式:
HC≡CMgBr
CAS号:
分子量:
129.24
Beilstein:
3600874
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22

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质量水平

反应适用性

reaction type: Grignard Reaction

浓度

0.5 M in THF

密度

0.94 g/mL at 25 °C

储存温度

2-8°C

SMILES字符串

Br[Mg]C#C

InChI

1S/C2H.BrH.Mg/c1-2;;/h1H;1H;/q;;+1/p-1

InChI key

HUGJUYPSXULVQQ-UHFFFAOYSA-M

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一般描述

乙炔基溴化镁溶液,也称溴化乙炔基镁,是一种格氏试剂,常用于合成聚合物和不饱和亚膦酸酯(phosphonite)。 [1] [2]

应用

乙炔基溴化镁溶液可用于:
  • 脂肪族聚合物的接枝。 [3]
  • 含蒽类物质(如1,8-二氯-10-(乙炔基)蒽)的合成。[4]
  • 炔烃复分解过程中炔烃组分的制备,以生成共轭二烯。[5]
  • 手性 α-(二苄氨基)醛的乙炔化。[6]
  • 乙炔基氮丙啶的合成。[7]
  • 烷基三氯锗烷和2-丁基三氯锗烷制备烷基(三乙炔基)锗烷。[8]
  • (+)-4-去甲氧基柔红霉素总合成中关键中间体的制备。[9]

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 2

靶器官

Respiratory system

补充剂危害

储存分类代码

4.3 - Hazardous materials which set free flammable gases upon contact with water

WGK

WGK 3

闪点(°F)

-20.2 °F

闪点(°C)

-29 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Grafting of functionalized polymer on porous silicon surface using Grignard reagent
FZ T,et al.
Applied Surface Science, 421, 82-88 (2017)
An enantioselective formal synthesis of 4-demethoxydaunomycin using the catalytic asymmetric ring opening reaction of meso-epoxide with p-anisidine
Sekine A, et al.
Tetrahedron, 58(1), 75-82 (2002)
Tandem enyne metathesis and Claisen rearrangement: a versatile approach to conjugated dienes of variable substitution patterns
Clark DA, et al.
Journal of the American Chemical Society, 128(49), 15632-15636 (2006)
Improved Access to 1, 8-Dichloro-10-(ethynyl) anthracene: A Useful Building Block for (Semi-) rigid Organic Frameworks
Jan-Hendrik L,et al.
Synthesis, 50, 2009-2018 (2018)
Highly heat resistant and thermo-oxidatively stable borosilane alkynyl hybrid polymers
Hua Z,et al.
Royal Society of Chemistry Advances, 5, 12161-12167 (2015)

相关内容

We carry a large variety of electrophiles and nucleophiles that are widely used in C–C bond-forming reactions. This group of products contains many organometallic reagents as well as commonly-used alkylating and acylating reagents.

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