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Merck

339792

Sigma-Aldrich

3,4-二丁氧基-3-环丁烯-1,2-二酮

98%

别名:

方酸二正丁酯

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5 G
$148.00
25 G
$628.00

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5 G
$148.00
25 G
$628.00

About This Item

线性分子式:
[CH3(CH2)3O]2C4(=O)2
CAS号:
分子量:
226.27
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$148.00


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质量水平

方案

98%

表单

liquid

折射率

n20/D 1.494 (lit.)

沸点

139 °C/0.5 mmHg (lit.)

密度

1.047 g/mL at 25 °C (lit.)

官能团

ether
ketone

SMILES字符串

CCCCOC1=C(OCCCC)C(=O)C1=O

InChI

1S/C12H18O4/c1-3-5-7-15-11-9(13)10(14)12(11)16-8-6-4-2/h3-8H2,1-2H3

InChI key

XBRWELTXMQSEIN-UHFFFAOYSA-N

一般描述

3,4-二丁氧基-3-环丁烯-1,2-二酮是方酸的二烷基酯。[1]

应用

3,4-二丁氧基-3-环丁烯-1,2-二酮用于合成新型半方酸染料,可用于在水性介质中进行高选择性Hg2+传感。[2]它也用于合成3-丁氧基-4-(1,3,3-三甲基-2,3-二氢-1H-2-吲哚基亚甲基)-3-环丁烯-1,2-二酮的中间体方酸染料。[3]

象形图

Exclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Eileen Tan et al.
International journal of dermatology, 41(11), 748-753 (2002-11-28)
Alopecia areata is believed to be an autoimmune condition with a worldwide occurrence. It usually presents as patchy, nonscarring hair loss. There is a paucity of clinical data in Asians. To study the epidemiology, clinical aspects, associations, and treatment of
Rachid Marhaba et al.
Journal of immunology (Baltimore, Md. : 1950), 179(8), 5071-5081 (2007-10-04)
Induction of a chronic eczema is a most efficient therapy for alopecia areata (AA). We had noted a reduction in regulatory T cells during AA induction and wondered whether regulatory T cells may become recruited or expanded during repeated skin
Kazumasa Morita et al.
The Journal of dermatology, 29(10), 661-664 (2002-11-16)
Topical immunotherapy is effective for severe alopecia areata. However, there are patients with alopecia areata refractory to topical immunotherapy alone. We tried SADBE (squaric acid dibutylester) topical immunotherapy combined with topical dry ice cryotherapy, carpronium chloride (a parasympathetic nerve stimulant)
C Ajith et al.
Journal of drugs in dermatology : JDD, 5(3), 262-266 (2006-04-01)
Immunotherapy with sqauric acid dibutyl ester (SADBE) is a well-accepted therapy for alopecia areata. To study efficacy, safety, and factors influencing the outcome in the treatment of alopecia areata. During a 4-year period, 70 patients of alopecia areata, unresponsive to
Aaron E Scott et al.
Toxicology and applied pharmacology, 183(1), 66-70 (2002-09-10)
The ability of chemical or pharmaceutical agents to induce allergic contact dermatitis (ACD) is of major health and regulatory concern. As such, tests to identify their sensitizing capacity, such as the guinea pig maximization test and the more recently developed

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