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Merck

242306

Sigma-Aldrich

氯甲酸烯丙酯

97%, for peptide synthesis

别名:

2-Propen-1-yl chloroformate, Allyloxycarbonyl chloride

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About This Item

线性分子式:
ClCOOCH2CH=CH2
CAS号:
分子量:
120.53
Beilstein:
773915
EC 号:
MDL编号:
UNSPSC代码:
12190000
PubChem化学物质编号:
NACRES:
NA.22
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产品名称

氯甲酸烯丙酯, 97%

蒸汽压

3.67 psi ( 20 °C)

质量水平

方案

97%

表单

liquid

折射率

n20/D 1.422 (lit.)

沸点

~27 °C/11 mmHg (lit.)

密度

1.134 g/mL at 20 °C (lit.)

应用

peptide synthesis

储存温度

−20°C

SMILES字符串

ClC(=O)OCC=C

InChI

1S/C4H5ClO2/c1-2-3-7-4(5)6/h2H,1,3H2

InChI key

CAEWJEXPFKNBQL-UHFFFAOYSA-N

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一般描述

氯甲酸烯丙酯是一种有机化合物,用于合成各种化合物,如烯丙基氨基甲酸酯和烯丙基碳酸酯。此外,它可用于制备α-烯丙基羰基和α, β-不饱和羰基。[1]

应用

氯甲酸烯丙酯可用于合成:
  • 组蛋白及其类似物。[2]
  • 由环硫酯(d,l-高半胱氨酸 硫内脂盐酸盐)生成Alloc-TL单体 (N-(烯丙氧基)羰基高半胱氨酸硫代内酯) 。[3]

警示用语:

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

87.8 °F - closed cup

闪点(°C)

31 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Carlos E Cuevas-Suárez et al.
Journal of the mechanical behavior of biomedical materials, 87, 148-154 (2018-08-03)
Over the past years, significant effort has been dedicated to synthesizing low-shrinking formulations, however, development of dental composites with low volumetric shrinkage continues to be challenging. The purpose of this study was to synthesize a bisphenol allylic derivate (BPhADAC) and
Palladium-catalyzed synthesis of substituted cycloheptane-1,4-diones by an asymmetric ring-expanding allylation (AREA).
Sabrina R Schulz et al.
Angewandte Chemie (International ed. in English), 46(21), 3966-3970 (2007-04-20)
Thiolactone-based polymers for formaldehyde scavenging coatings
Resetco C, et al.
European Polymer Journal, 82, 166-174 (2016)
Allyl Chloroformate
Herrinton PM
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2001)
Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes
Maity SK, et al.
Nature Protocols, 11(12), 2293-2322 (2017)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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