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Merck

225916

Sigma-Aldrich

苄基氯化镁 溶液

2.0 M in THF

别名:

(Phenylmethyl)magnesium chloride, Benzylchloromagnesium, Chloro(phenylmethyl)magnesium

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100 ML
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About This Item

线性分子式:
C6H5CH2MgCl
CAS号:
分子量:
150.89
Beilstein:
878506
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22

$134.00


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质量水平

反应适用性

reaction type: Grignard Reaction

浓度

2.0 M in THF

密度

1.031 g/mL at 25 °C

官能团

phenyl

SMILES字符串

Cl[Mg]Cc1ccccc1

InChI

1S/C7H7.ClH.Mg/c1-7-5-3-2-4-6-7;;/h2-6H,1H2;1H;/q;;+1/p-1

InChI key

NRAFPLGJPPJUNB-UHFFFAOYSA-M

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一般描述

氯苄镁是一种有机金属化合物,可用作Lewis酸和强碱。[1]

应用

苄基氯化镁(格利雅试剂)可用作烷基化试剂:
  • 烷基化喹啉基功能化Cp−铬(III)复合物,以作为前体用于制备活性烯烃聚合催化剂。[2]
  • 合成2,3-二取代苯并吡喃-4-酮[3]、6-氯代-8- 甲基嘌呤衍生物[4]和苯基丙氨酸衍生物。[5]

警示用语:

Danger

危险分类

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

靶器官

Central nervous system, Respiratory system

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

1.4 °F - closed cup

闪点(°C)

-17 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dichotomy in regioselective cross-coupling reactions of 6, 8-dichloropurines with phenylboronic acid and methylmagnesium chloride: synthesis of 6, 8-disubstituted purines
Hocek M, et al.
Synthesis, 2004(06), 889-894 (2004)
Benzylmagnesium Chloride
Herman G
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Quinolyl-functionalised Cp-chromium polymerisation catalysts: synthesis and crystal structures of alkylation products
Enders M, et al.
Journal of Organometallic Chemistry, 687(1), 125-130 (2003)
A facile three-step synthesis of 1, 2-amino alcohols using the Ellman homochiral tert-butylsulfinamide
Barrow JC, et al.
Tetrahedron Letters, 42(11), 2051-2054 (2001)
A novel synthesis of 2, 3-disubstituted benzopyran-4-ones and application to the solid phase
Harikrishnan LS and Showalter HD H
Tetrahedron, 56(4), 515-519 (2000)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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