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![苯并[a]芘 ≥96% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/253/820/be96d879-1811-46c0-8f11-612019691c2d/640/be96d879-1811-46c0-8f11-612019691c2d.png)
化驗
≥98%
mp
122-123 °C (lit.)
SMILES 字串
Cc1c2ccccc2c(C)c3c1ccc4ccccc34
InChI
1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3
InChI 密鑰
ARSRBNBHOADGJU-UHFFFAOYSA-N
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應用
最有效的多环芳烃致癌物之一。
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产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Carc. 1B
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
A Garg et al.
International journal of oncology, 3(2), 185-189 (1993-08-01)
The ability of the mammary procarcinogen 7,12-dimethylbenz(a)anthracene (DMBA) to induce the expression of selected molecular and cellular biomarkers for preneoplastic transformation is examined in a newly developed, immortalized but nontumorigenic mammary epithelial cell line C57/MG. This cell line is established
J DiGiovanni et al.
Drug metabolism reviews, 11(1), 61-101 (1980-01-01)
As the result of rapidly developing technological advances, our understanding of the biotransformation and bioactivation of 7, 12-DMBA has increased markedly in recent years. In terms of the metabolic conversion of this polynuclear aromatic hydrocarbon to reactive mutagen/carcinogens, the "bay
Ramar Perumal Samy et al.
PloS one, 7(12), e48514-e48514 (2013-01-04)
Breast cancer is the most common cancer among women. To date, improvements in hormonal and cytotoxic therapies have not yet led to a sustained remission or cure. In the present study, we investigated the in vitro and in vivo antitumor
Anthony J Apostoli et al.
International journal of cancer, 134(5), 1055-1066 (2013-08-13)
Breast cancer is the leading cause of new cancer diagnoses among women. Using peroxisome proliferator-activated receptor (PPAR)γ((+/-)) mice, we showed normal expression of PPARγ was critical to stop 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast tumorigenesis. PPARγ is expressed in many breast cell types
E Hallberg
Journal of biochemical toxicology, 5(2), 71-90 (1990-01-01)
The adrenal cortex contains high amounts of detoxifying enzymes, as well as generators and protectors of reactive oxygen species. The high content of cytochrome P-450 enzymes in the adrenal cortex together with its remarkable tendency to accumulate hydrophobic substances probably
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