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Merck

94956

Sigma-Aldrich

二氧化乙烯基环己烯

purum, suitable for electron microscopy, mixture of isomers, ≥96.0% (GC)

别名:

4-乙烯基-1-环己烯二环氧化物, 3-环氧乙基-7-氧杂二环[4,1,0]庚烷

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About This Item

经验公式(希尔记法):
C8H12O2
CAS号:
分子量:
140.18
Beilstein:
106071
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.25

等級

purum

化驗

≥96.0% (GC)

形狀

liquid

技術

electron microscopy: suitable

折射率

n20/D 1.477 (lit.)
n20/D 1.479

bp

230-232 °C (lit.)

密度

1.094 g/mL at 25 °C (lit.)

SMILES 字串

C1CC2OC2CC1C3CO3

InChI

1S/C8H12O2/c1-2-6-7(10-6)3-5(1)8-4-9-8/h5-8H,1-4H2

InChI 密鑰

OECTYKWYRCHAKR-UHFFFAOYSA-N

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應用

乙烯基环己烯二氧化物(VCD)可用于研究和了解其对卵巢卵泡的影响和对上皮分化的影响。

相關產品

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

224.6 °F - closed cup

閃點(°C)

107 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Melissa J Romero-Aleshire et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 297(3), R587-R592 (2009-05-15)
Factors comprising the metabolic syndrome occur with increased incidence in postmenopausal women. To investigate the effects of ovarian failure on the progression of the metabolic syndrome, female B(6)C(3)F(1) mice were treated with 4-vinylcyclohexene diepoxide (VCD) and fed a high-fat (HF)
Tracey A Van Kempen et al.
Brain research, 1379, 176-187 (2011-01-08)
Current rodent models of menopause fail to adequately recapitulate the menopause transition. The intact aging model fails to achieve very low estrogen levels, and the ovariectomy model lacks a perimenopause phase. A new rodent model of accelerated ovarian failure (AOF)
Lida P Hariri et al.
Cancer biology & therapy, 10(5), 438-447 (2010-11-26)
Determining if an ovarian mass is benign or malignant is an ongoing clinical challenge. The development of reliable animal models provides means to evaluate new diagnostic tools to more accurately determine if an ovary has benign or malignant features. Although
Aileen F Keating et al.
Biology of reproduction, 84(4), 743-751 (2010-11-16)
4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that specifically destroys primordial and small primary follicles in the ovaries of rats and mice, is thought to target an oocyte-expressed tyrosine kinase receptor, Kit. This study compared the temporal effect of VCD on
Aileen F Keating et al.
Toxicology and applied pharmacology, 247(2), 71-75 (2010-06-15)
The occupational chemical 4-vinylcyclohexene diepoxide (VCD) selectively destroys ovarian small pre-antral follicles in rats and mice via apoptosis. Detoxification of VCD can occur through glutathione conjugation, catalyzed by glutathione S-transferase (GST) enzymes. Further, GST class pi (GSTp) can negatively regulate

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