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Merck

202673

Sigma-Aldrich

氧化砷(III)

99.995% trace metals basis

别名:

ATO, 三氧化二砷;, 三氧化二砷, 亚砷酸

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About This Item

经验公式(希尔记法):
As2O3
CAS号:
分子量:
197.84
EC號碼:
MDL號碼:
分類程式碼代碼:
12161600
eCl@ss:
38080102
PubChem物質ID:
NACRES:
NA.22

化驗

99.995% trace metals basis

形狀

powder

反應適用性

core: arsenic
reagent type: catalyst

SMILES 字串

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI 密鑰

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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一般說明

氧化砷(ATO)是一种无机形式的砷,可用作治疗急性早幼粒细胞白血病(APL)患者的治疗化合物。目前正在开发许多药物传递方法,利用纳米技术克服由于快速从血液中清除而导致生物利用度差的问题。

應用


  • Electrochemical detection applications: A study on La-based perovskites incorporated with functionalized carbon nanofibers highlights the use of arsenic trioxide for the electrochemical detection of roxarsone in water and food samples, providing a method to improve safety and environmental monitoring (John Felix MA et al., 2024).

  • Antiproliferative effects in cancer research: Research demonstrates the inhibitory effects of arsenic trioxide, combined with metformin, on KG1a cell proliferation, suggesting its potential utility in developing antineoplastic strategies (Huang-Li WH et al., 2024).

  • Environmental remediation: A review on manganese oxide-based materials for arsenic removal discusses the application of arsenic trioxide in environmental remediation, focusing on the effectiveness and advancements in arsenic decontamination technologies (Younas M et al., 2024).

訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

標靶器官

Respiratory system,Cardio-vascular system,Gastrointestinal tract

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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A facile route to core?shell nanoparticulate formation of arsenic trioxide for effective solid tumor treatment.
Zhang Z, et al.
Nanoscale, 8(7), 4373-4380 (2016)
Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers.
Akhtar A, et al.
Journal of biomedical research, 31(3), 177-177 (2017)
Silica nanovehicles endow arsenic trioxide with an ability to effectively treat cancer cells and solid tumors.
Zhao Z, et al.
Journal of Materials Chemistry, 2(37), 6313-6323 (2014)
Ruoshi Xu et al.
Bone research, 6, 33-33 (2018-11-28)
How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has

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