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153818

2-金刚烷胺盐酸盐

Name: 2-金刚烷胺 盐酸盐
Brand: ALDRICH

99%

别名:

2-Adamantanamine 盐酸盐, 2-氨基金刚烷盐酸盐

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About This Item

经验公式（希尔记法）:

C₁₀H₁₇N · HCl

CAS号:

10523-68-9

分子量:

187.71

Beilstein:

4297901

EC 号:

234-074-2

MDL编号:

MFCD00074743

UNSPSC代码:

12352100

PubChem化学物质编号:

24849376

NACRES:

NA.22

价格与库存信息目前不能提供

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质量水平

100

方案

99%

表单

solid

mp

>300 °C (lit.)

SMILES字符串

Cl.NC1[C@@H]2C[C@H]3C[C@@H](C2)C[C@@H]1C3

InChI

1S/C10H17N.ClH/c11-10-8-2-6-1-7(4-8)5-9(10)3-6;/h6-10H,1-5,11H2;1H/t6-,7+,8-,9+,10?;

InChI key

WLDWDRZITJEWRJ-ZDAMNCSYSA-N

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一般描述

The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied[1].

应用

2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2′-(carboxymethoxime)-olivomycin I[2].

象形图

GHS07

警示用语：

Warning

危险声明

H315,H319,H335

预防措施声明

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].

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The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated. Bromantane leads to decreases in

Development and validation of an LC-MS/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent.

Alina A Okhina et al.

Journal of pharmaceutical and biomedical analysis, 180, 113039-113039 (2019-12-23)

A method of quantitative determination of camphecene, a new anti-influenza agent, in rat blood plasma based on LC-MS/MS was developed, validated and used to study the distribution of the agent between blood cells and blood plasma. The method was validated

Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.

Yasuhiko Higashi et al.

Biomedical chromatography : BMC, 20(5), 423-428 (2005-09-15)

Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine hydrochloride (rimantadine) and 3,5-dimethyl-1-adamantanamine hydrochloride (memantine)] in phosphate-buffered saline (pH 7.4) after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) was developed. Phosphate-buffered saline samples

Inhibition of lymphocyte proliferation by amantadine and its isomer, 2-aminoadamantane; impact on Lyt-2+ T cells while sparing L3T4+ T cells.

C Clark et al.

Immunopharmacology, 21(1), 41-50 (1991-01-01)

The present in vitro investigations on amantadine (AmTd) and its isomer 2-aminoadamantane (2-NH2-Adam), and the corresponding analogs, 1-nitroadamantane (1-NO2-Adam) and 2-nitroadamantane (2-NO2-Adam), were undertaken to gain information about molecular features that might have a dominant role in inhibiting T lymphocyte

Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.

Anna N Tevyashova et al.

The Journal of antibiotics, 62(1), 37-41 (2009-01-10)

A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine hemihydrochloride gave the key intermediate, 2'-carboxymethoxime-olivomycin I, which

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2-金刚烷胺盐酸盐