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质量水平
方案
98%
表单
solid
mp
219-220 °C (dec.) (lit.)
溶解性
ethanol: soluble 50 mg/mL
官能团
carboxylic acid
ketone
SMILES字符串
OC(=O)C(=O)Cc1ccc(O)cc1
InChI
1S/C9H8O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,10H,5H2,(H,12,13)
InChI key
KKADPXVIOXHVKN-UHFFFAOYSA-N
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一般描述
可通过质谱的多反应监测(MRM)灵敏方法对猪肉和伊比利亚火腿样品中的4-羟基苯基丙酮酸进行测定[1]。
应用
<ul>
<li><strong>缺血性卒中血清生物标志物的鉴定:</strong>研究使用4-羟基苯丙酮酸作为区分高血压缺血性卒中(IS)患者与健康个体和高血压患者的潜在诊断生物标志物(Zhao et al., 2023)。</li>
</ul>
<li><strong>缺血性卒中血清生物标志物的鉴定:</strong>研究使用4-羟基苯丙酮酸作为区分高血压缺血性卒中(IS)患者与健康个体和高血压患者的潜在诊断生物标志物(Zhao et al., 2023)。</li>
</ul>
制备说明
50 gm的4-羟基苯基丙酮酸溶于1 mL乙醇中可得到澄清的淡黄色溶液。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Density functional calculations using the B3LYP functional has been used to study the reaction mechanism of 4-hydroxyphenylpyruvate dioxygenase. The first part of the catalytic reaction, dioxygen activation, is found to have the same mechanism as in alpha-ketoglutarate-dependent enzymes; the ternary
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