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00820580

Verbascoside

primary reference standard

Synonym(s):

Acetoside, Kusaginin

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About This Item

Empirical Formula (Hill Notation):
C29H36O15
CAS Number:
61276-17-3
Molecular Weight:
624.59
MDL number:
MFCD00221751
UNSPSC Code:
85151701
PubChem Substance ID:
329747147
NACRES:
NA.24

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

InChI key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

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General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference Strandard in the analysis of herbal medicinal products

Biochem/physiol Actions

Phenylethanoid glycoside. Antioxidant and antiproliferative.

Other Notes

This compound is commonly found in plants of the genus: echinacea plantago

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI02851
HWI02413-2
HWI02413-1
HWI02413
HWI01068-2

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Wei-gao Pan et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 46(4), 422-427 (2011-07-14)
Using a bioassay-guided fractionation technique, two compounds were isolated from the roots of Incarvillea younghusbandii Sprague through silica gel, reverse-phase C18 column chromatography and reverse-phase HPLC. Their structures were identified as acteoside (1) and isoacteoside (2) by ESI-MS, GC-MS, 1D-
Ho Sun Song et al.
Archives of pharmacal research, 35(5), 905-910 (2012-05-31)
The aim of this study was to investigate whether acteoside isolated from Clerodendron trichotomum Thunberg may act as a selective inhibitor of phospholipase A(2) in RBL-2H3 cells. Acteoside dose-dependently inhibited 0.5 μM melittin-induced release of [(3)H]arachidonic acid, which was due
Hong-Quan Wang et al.
Neurotoxicity research, 21(4), 368-378 (2011-12-08)
Our previous study has shown that acteoside, an antioxidative phenylethanoid glycoside, protect against beta-amyloid (Aβ)-induced cytotoxicity in vitro. However, the precise protective mechanisms remains unclear. Heme oxygenase-1 (HO-1) is a crucial factor in the response to oxidative injury, protecting neurons
Young-Ok Son et al.
The Journal of pharmacy and pharmacology, 63(10), 1309-1319 (2011-09-09)
Acteoside is a phenylpropanoid glycoside extracted from the leaves of Rehmannia glutinosa that displays various biological activities. In this study, we tested the effects of acteoside on tyrosinase activity and melanin biosynthesis in B16F10 melanoma cells. We also explored molecular
Jun Xie et al.
Food chemistry, 135(4), 2536-2541 (2012-09-18)
Echinacoside and verbascoside possess a spectrum of significant beneficial bioactivities. A new method of preparative high-speed counter-current chromatography for rapid separation and purification of verbascoside from the leaves of Penstemon barbatus (Cav.) Roth was introduced. The solvent system employed here
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