V4015

Verbascoside

≥99% (HPLC)

• Synonym(s): Acetoside, Kusaginin
• Empirical Formula (Hill Notation): C₂₉H₃₆O₁₅
• CAS Number: 61276-17-3
• Molecular Weight: 624.59
• NACRES: NA.25
• PubChem Substance ID: 329829047
• UNSPSC Code: 12352200
• MDL number: MFCD00221751

Properties

• Quality Segment: 200
• assay: ≥99% (HPLC)
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: room temp
• SMILES string: C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1
• InChI key: FBSKJMQYURKNSU-ZLSOWSIRSA-N

Description

General description

Verbascoside, also known as acteoside, is a hydrophilic plant compound first isolated from mullein (Verbascum sinuatum L.). The chemical structure of verbascoside comprises hydroxyphenylethyl and cinnamic acid moieties bound to a β-glucopyranose via a glycosidic bond.

Application

Verbascoside has been used:

• as a reference standard for high-performance liquid chromatography (HPLC) analysis
• as a reference standard for detection of phenolic compounds in olive mill wastewater and pomace by high-performance liquid chromatography (HPLC)-diode-array detector (DAD)-qTOF system
• to test its anti-viral activity against respiratory syncytial virus (RSV) in HEP2 cells and A549 cells

Biochem/physiol Actions

Phenylethanoid glycoside. Antioxidant and antiproliferative.

Verbascoside has anti-inflammatory and photoprotective properties. It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity. Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable