1138008

Clindamycin phosphate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Clindamycin 2-phosphate, Clindamycin 2-dihydrogen phosphate
• Empirical Formula (Hill Notation): C₁₈H₃₄ClN₂O₈PS
• CAS Number: 24729-96-2
• Molecular Weight: 504.96
• NACRES: NA.24
• PubChem Substance ID: 329749424
• UNSPSC Code: 41116107
• MDL number: MFCD07793328

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: clindamycin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC([C@H](C)Cl)C2O[C@H](SC)[C@H](OP(O)(O)=O)[C@@H](O)[C@H]2O
• InChI: 1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12?,13+,14-,15?,16+,18+/m0/s1
• InChI key: UFUVLHLTWXBHGZ-MWBQRTRKSA-N

Description

General description

Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.[1]

Application

Clindamycin phosphate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Clindamycin Phosphate Gel
• Clindamycin Phosphate Vaginal Cream
• Clindamycin Phosphate Topical Suspension
• Clindamycin Phosphate Vaginal Inserts
• Clindamycin Phosphate Topical Solution
• Clindamycin Injection

Biochem/physiol Actions

Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.
Mode of Action: Inhibits protein synthesis in bacterial by binding the 50s ribosomal subunit.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Antibacterial and antiprotozoal antibiotic of the licosamide class.

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319,H362
• pcodes: P260 - P263 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Lact. - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable