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Captopril

Name: Captopril
Brand: USP
Price: 416 USD
Availability: InStock

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline

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Pack Size	SKU	Availability	Price
200 mg		Available to ship TODAYfromMILWAUKEE	$416.00

About This Item

Empirical Formula (Hill Notation):

C₉H₁₅NO₃S

CAS Number:

62571-86-2

Molecular Weight:

217.29

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749226

MDL number:

MFCD00168073

Beilstein/REAXYS Number:

477887

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

captopril

manufacturer/tradename

USP

mp

104-108 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O

InChI

1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1

InChI key

FAKRSMQSSFJEIM-RQJHMYQMSA-N

Gene Information

human ... ACE(1636)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Captopril USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Captopril and Hydrochlorothiazide Tablets
Captopril Compounded Oral Solution
Captopril Compounded Oral Suspension
Captopril Tablets

Biochem/physiol Actions

Angiotensin converting enzyme inhibitor. Inhibits the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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1 of 1

This Item	C0430000	BP538	PHR1307
USP 1091200 Captopril	C0430000 Captopril	BP538 Captopril	Supelco PHR1307 Captopril
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)	Gene Information human ... ACE(1636)
mp 104-108 °C (lit.)	mp 104-108 °C (lit.)	mp 104-108 °C (lit.)	mp 104-108 °C (lit.)

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pictograms

GHS08

signalword

Danger

hcodes

H341,H360F

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Muta. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Molecular regulation of the renin-angiotensin system in haemodialysis patients.

Johannes J Kovarik et al.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 30(1), 115-123 (2014-08-12)

Blockade of the renin-angiotensin system (RAS) exerts beneficial effects in patients with mild-to-moderate chronic kidney disease, yet evidence suggesting a similar benefit in haemodialysis (HD) patients is not available. Furthermore, knowledge of the effects of RAS blockade on systemic RAS

Captopril as a potential inhibitor of lung tumor growth and metastasis.

Samir Attoub et al.

Annals of the New York Academy of Sciences, 1138, 65-72 (2008-10-08)

Lung cancer is the most common form of cancer in the world, and 90% of patients die from their disease. The angiotensin converting enzyme (ACE) inhibitors are used widely as antihypertensive agents, and it has been suggested that they decrease

Captopril-induced jaundice: report of 2 cases and a review of 13 additional reports in the literature.

A Schattner et al.

The American journal of the medical sciences, 322(4), 236-240 (2001-10-27)

Two elderly patients, treated with captopril for left ventricular dysfunction and diabetes, developed severe cholestatic jaundice for which no alternative explanation could be found. The jaundice resolved completely after discontinuation of the drug. A review of the literature identifies a

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Global Trade Item Number

SKU	GTIN
1091200-200MG	04061838687937

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