Transient receptor potential-canonical 3 (TRPC3) is a member of TRP superfamily. It is mainly expressed in brain. The TRPC3 gene is mapped to human chromosome 4.
Immunogen
peptide corresponding to amino acid residues 822-835 of mouse TRPC3.
Biochem/physiol Actions
TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo. TRPC3 plays a key role in a wide spectrum of Ca2+ signaling mechanisms. Elevated expression of TRPC3 has been observed in spontaneously hypertensive rats (SHR).
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Local anesthetics, particularly potent long acting ones such as bupivacaine, can cause cardiotoxicity by inhibiting sodium ion channels; however, the impact of left ventricular hypertrophy on the cardiotoxicity and the underlying mechanisms remain undetermined. Transient receptor potential canonical (TRPC) channels
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
