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T3165

7-Methoxy-4-(trifluoromethyl)coumarin

≥99% (TLC)

Synonym(s):

Methyl 4-(trifluoromethyl)umbelliferyl ether

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Pack SizeSKUAvailabilityPrice
100 mg
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$827.00

About This Item

Empirical Formula (Hill Notation):
C11H7F3O3
CAS Number:
Molecular Weight:
244.17
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
225039

$827.00


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Quality Segment

assay

≥99% (TLC)

form

powder

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

fluorescence

λex 333 nm; λem 416 nm in methanol

SMILES string

COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3

InChI key

HAZHUELNIGDYQH-UHFFFAOYSA-N

Application

7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay[1] and aromatase assay.[2]

Biochem/physiol Actions

The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.[1]

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This Item
T2803A430264951
assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥98.0% (TLC)

solubility

acetone: 50 mg/mL, clear, colorless to faintly yellow

solubility

chloroform: 100 mg/mL, clear, colorless (Soluble in chloroform, methanol, and DMSO.)

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

solubility

DMF: soluble, acetonitrile: soluble, alcohols: soluble, chloroform: soluble

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

solid

fluorescence

λex 333 nm; λem 416 nm in methanol

fluorescence

λex 333 nm; λem 415 nm in methanol

fluorescence

λex 325 nm; λem 389 nm in ethanol

fluorescence

λex 350 nm; λem 385 nm (Reaction product), λex 350 nm; λem 385 nm in chloroform


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Global Trade Item Number

SKUGTIN
T3165-100MG04061837343841

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