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S1876

Sigma-Aldrich

D-Sorbitol

≥98% (GC)

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein/REAXYS Number:
1721899
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

≥98% (GC)

form

powder or crystals

color

white

useful pH range

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: 200 mg/mL, clear, colorless

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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Application

May be used for washing spheroplasts and in isoelectric focusing to minimize endoosmotic flow in agarose gels. May be used to induce osmotic stress.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Isoelectric focusing.
D E Garfin
Methods in enzymology, 182, 459-477 (1990-01-01)
Preparation of extracts from yeast.
S M Jazwinski
Methods in enzymology, 182, 154-174 (1990-01-01)
Kartik A Shah et al.
Biotechnology and bioengineering, 112(12), 2624-2629 (2015-06-03)
Monoclonal antibodies (mAbs) that bind and neutralize human pathogens have great therapeutic potential. Advances in automated screening and liquid handling have resulted in the ability to discover antigen-specific antibodies either directly from human blood or from various combinatorial libraries (phage
G Molino et al.
The Journal of laboratory and clinical medicine, 131(5), 393-405 (1998-05-30)
D-Sorbitol (SOR) is safe, is easy to measure, and has an exceptionally high extraction ratio in the normal liver of 0.93+/-0.05 (mean+/-SD). Together with the general interest in hepatic hemodynamics, these facts motivated us to review the usefulness of this
Shahram Attarian et al.
Orphanet journal of rare diseases, 9, 199-199 (2014-12-19)
Charcot-Marie-Tooth type 1A disease (CMT1A) is a rare orphan inherited neuropathy caused by an autosomal dominant duplication of a gene encoding for the structural myelin protein PMP22, which induces abnormal Schwann cell differentiation and dysmyelination, eventually leading to axonal suffering

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