S104

(−)-Scopolamine hydrobromide trihydrate

• Synonym(s): Hyoscine hydrobromide, Scopine tropate
• Empirical Formula (Hill Notation): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS Number: 6533-68-2
• Molecular Weight: 438.31
• UNSPSC Code: 41116107
• Beilstein/REAXYS Number: 6100669
• MDL number: MFCD00150066

Properties

• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 195-199 °C (dry matter) (lit.)
• format: neat
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist.

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges