This product is soluble in chloroform:methanol (95:5 v/v) at a concentration of 50 mg/mL. It will likely form a suspension or emulsion in deionized water at a concentration of 1 mg/mL or higher.
P5660
3-sn-Phosphatidyl-L-serine sodium salt from bovine brain
≥95% (TLC), Procoagulant and Hemostatic regulator, powder
Synonym(s):
1,2-Diacyl-sn-glycero-3-phospho-L-serine, L-α-Phosphatidyl-L-serine sodium salt
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | Check Cart for Availability | $462.00 | |
| 25 mg | Check Cart for Availability | $1,850.00 $1,572.50 | |
| 100 mg | Check Cart for Availability | $4,430.00 |
About This Item
Assay:
≥95% (TLC)
Form:
powder
Product Name
3-sn-Phosphatidyl-L-serine sodium salt from bovine brain, ≥95% (TLC)
Quality Segment
assay
≥95% (TLC)
form
powder
storage temp.
−20°C
SMILES string
[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1
InChI key
SJRBMGBLPUBGJL-MBAWARMDSA-M
General description
Phosphatidylserine is an anionic phospholipid, which is found on the plasma membrane. Exposure of phosphatidylserine on the surface of plasma membrane stimulates the removal of apoptotic and red blood cells. It regulates the production of thrombin and maintains hemostasis.
Application
3-sn-Phosphatidyl-L-serine sodium salt from bovine brain has been used as a glycosylphosphatidylinositol (GPI)-anchor control.
Biochem/physiol Actions
A slowly metabolized structural phospholipid found mainly in gray matter.
Preparation Note
Washed with EDTA and converted to a sodium salt.
Disclaimer
Solutions exposed to room temperature will decompose about 0.5% per day.
1 of 1
This Item | ||
|---|---|---|
| assay ≥95% (TLC) | assay ≥98% (TLC) | assay ≥97% |
| form powder | form lyophilized powder | form powder |
| Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5660-5MG | 04061834392194 |
| P5660-100MG | 04061834392170 |
| P5660-25MG | 04061834392187 |
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What is Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain, soluble in?
1 answer-
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What is the molecular weight of Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain?
1 answer-
The molecular weight of this compound is approximately 812.1 g/mole. This molecular weight assumes that stearoyl and oleoyl are the prodimant fatty acids in the compound. Phosphatidylserine may have a number of different fatty acid residues associated with it. Our analyses of multiple lots of phosphatidylserine identified average fatty acid percentages of approximately 40% for stearic acid and 30% for oleic acid.
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What is Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt, commonly used for?
1 answer-
Phosphatidylserine is important in enzymatic assays of purified protein kinase C. During activation of this enzyme, as part of the signal transduction process, phosphatidylserine, which is located on the inside of cellular plasma membranes, binds to cysteine residue domains on protein kinase C. Phosphatidylserine can be used as a standard in thin-layer chromatography and for artificial membrane studies such as in lipsome research.
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Is 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain available in solution?
1 answer-
Yes. Product No. P6641 is a ready-to-use solution of phosphatidylserine in a chloroform:methanol mixture.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Do you have any inhibitors for Protein Kinase C (PKC)?
1 answer-
Yes. Two examples are Product No. C6303 (Calphostin C from Cladosporium cladosporioides) and Product No. C2932 (Chelerythrine chloride).
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What is the solution stability of Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain?
1 answer-
Solutions can be divided into aliquots and stored at -20 °C. We have no information as to how long the solutions will be stable. Solution stability is enhanced when the compound is protected from oxygen, because the unsaturated fatty acids are subject to oxidation. To protect from oxidation, dissolve the compound in solvents in which oxygen has been removed and replaced with an inert gas such as nitrogen or argon.
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