Key Documents

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

Name: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride
Brand: SIGMA
Price: 139 USD
Availability: InStock

≥97% (GC), MAO-A inhibitor, powder

Synonym(s):

Clorgyline

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Pack Size	Availability	Price
50 mg	Available to ship TODAYfromMILWAUKEE	$139.00
100 mg	Available to ship TODAYfromMILWAUKEE	$237.00
500 mg	Available to ship TODAYfromMILWAUKEE	$768.00

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₅Cl₂NO · HCl

CAS Number:

17780-75-5

Molecular Weight:

308.63

NACRES:

NA.77

PubChem Substance ID:

24278179

UNSPSC Code:

12352116

EC Number:

241-760-5

MDL number:

MFCD00052012

Assay:

≥97% (GC)

Form:

powder

$139.00

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Properties

Product Name

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)

Quality Segment

100

assay

≥97% (GC)

form

powder

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C

InChI

1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

InChI key

BBAZDLONIUABKI-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128)
rat ... Maoa(29253), Maob(25750)

Description

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

in MAO-A biochemical assay[1]
to study its effects on the transit of serotonin (5-HT) in the human placenta explants[2]
to study its effects on human prostate cancer cells[3]

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item	P8511	E2895	A3085
Sigma-Aldrich M3778 N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride	Sigma-Aldrich P8511 trans-2-Phenylcyclopropylamine hydrochloride	Sigma-Aldrich E2895 (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide	Sigma-Aldrich A3085 5-(N-Ethyl-N-isopropyl)amiloride
assay ≥97% (GC)	assay ≥97% (TLC)	assay ≥98%	assay ≥98% (TLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C
solubility DMSO: 10 mg/mL, clear, colorless to faintly yellow	solubility ethanol: 50 mg/mL, clear to slightly hazy	solubility DMSO: 10 mg/mL, clear, colorless to faintly yellow	solubility methanol: 9.80-10.20 mg/mL, clear, light yellow to yellow
Gene Information human ... MAOA(4128) rat ... Maoa(29253), Maob(25750)	Gene Information human ... MAOA(4128), MAOB(4129)	Gene Information -	Gene Information human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548), SLC9A5(6553) mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278) rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784), Slc9a4(24785)