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M1568

Mannose triflate

For PET imaging, ≥98% (TLC)

Synonym(s):

β-D-Mannopyranose 1,3,4,6-tetra-O-acetate 2-O-trifluoromethanesulfonate, 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose, Mannose triflate, TATM

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Pack SizeSKUAvailabilityPrice
20 mg
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$30.30
40 mg
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$53.20
100 mg
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$82.30
$57.61
10 x 25 mg
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$166.00

About This Item

Empirical Formula (Hill Notation):
C15H19F3O12S
CAS Number:
92051-23-5
Molecular Weight:
480.36
UNSPSC Code:
41116107
NACRES:
NA.12
PubChem Substance ID:
24896669
MDL number:
MFCD00012353
Beilstein/REAXYS Number:
4341413
Assay:
≥98% (TLC)
Form:
powder

$30.30

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Quality Segment

200

assay

≥98% (TLC)

form

powder

technique(s)

PET imaging: suitable

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1

InChI key

OIBDVHSTOUGZTJ-PEBLQZBPSA-N

General description

Mannose triflate is a glucose analogue.

Application

Mannose triflate is a well-known precursor for 18F-FDG synthesis for PET applications. The binding of 18F to the mannose triflate has been carried out via SN2 nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

Other Notes

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

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This Item
M6633M2069A7562
Mannose triflate For PET imaging, ≥98% (TLC)

Sigma-Aldrich

M1568

Mannose triflate

α-D-Mannose pentaacetate

Sigma-Aldrich

M6633

α-D-Mannose pentaacetate

D-(+)-Mannose ≥99% (GC), wood

Sigma-Aldrich

M2069

D-(+)-Mannose

Acetobromo-α-D-galactose ≥93% (TLC)

Sigma-Aldrich

A7562

Acetobromo-α-D-galactose

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥99% (GC)

assay

≥93% (TLC)

technique(s)

PET imaging: suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

dry ice

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000454895
0000454895
0000417282
0000417283
0000419879

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Related Content

Ren Iwata et al.
Journal of labelled compounds & radiopharmaceuticals, 61(7), 540-549 (2018-03-10)
High specific activity is often a significant requirement for radiopharmaceuticals. To achieve that with fluorine-18 (18 F)-labeled probes, it is mandatory to start from no-carrier-added fluoride and to reduce to a minimum the amount of precursor in order to decrease
Shane B Claggett et al.
EJNMMI research, 3(1), 53-53 (2013-07-17)
Many automated radiosynthesizers for producing positron emission tomography (PET) probes provide a means for the operator to create custom synthesis programs. The programming interfaces are typically designed with the engineer rather than the radiochemist in mind, requiring lengthy programs to
Padgett, H., et al.
Applied Radiation and Isotopes, 40, 433-433 (1989)
View All Related Papers

Global Trade Item Number

SKUGTIN
M1568-40MG04061833290163
M1568-20MG04061833290149
M1568-25MG04061833290156
M1568-100MG04061833285411
M1568-10X25MG04061833247488

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