L2407

Luzindole

≥90%, melatonin receptor antagonist

• Synonym(s): N-Acetyl-2-benzyltryptamine, N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide
• Empirical Formula (Hill Notation): C₁₉H₂₀N₂O
• CAS Number: 117946-91-5
• Molecular Weight: 292.37
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896315
• NACRES: NA.77
• MDL number: MFCD00672498
• Assay: ≥90%

Properties

• Product Name: Luzindole, ≥90%
• Quality Segment: 200
• assay: ≥90%
• solubility: DMSO: 5 mg/mL
• storage temp.: −20°C
• SMILES string: CC(=O)NCCc1c(Cc2ccccc2)[nH]c3ccccc13
• InChI: 1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
• InChI key: WVVXBPKOIZGVNS-UHFFFAOYSA-N
• Gene Information: human ... MTNR1A(4543), MTNR1B(4544)

Description

Application

Luzindole has been used as a MT1/MT2 receptor antagonist to detect the role of the melatonin receptor in neutrophil migration

Biochem/physiol Actions

Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.

Features and Benefits

This compound is featured on the Melatonin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)