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L135

L-741,626

≥98% (HPLC)

Synonym(s):

(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole

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Pack SizeSKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$179.00
$152.15

About This Item

Empirical Formula (Hill Notation):
C20H21ClN2O
CAS Number:
81226-60-0
Molecular Weight:
340.85
NACRES:
NA.77
PubChem Substance ID:
24278529
UNSPSC Code:
12352200
MDL number:
MFCD00953632
Assay:
≥98% (HPLC)
Form:
powder

$152.15

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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥20 mg/mL, ethanol: 24 mg/mL, H2O: insoluble

storage temp.

room temp

SMILES string

OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4

InChI

1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2

InChI key

LLBLNMUONVVVPG-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815)

Application

L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells.[1] It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.[2]

Biochem/physiol Actions

L-741,626 is a selective dopamine (D2) receptor antagonist.[3]

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Show Differences

1 of 1

This Item
SML0369SML1804H1512
L-741,626 ≥98% (HPLC)

Sigma-Aldrich

L135

L-741,626

CID-2011756 ≥98% (HPLC)

Sigma-Aldrich

SML0369

CID-2011756

AM4113 ≥98% (HPLC)

Sigma-Aldrich

SML1804

AM4113

Haloperidol powder

Sigma-Aldrich

H1512

Haloperidol

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

storage temp.

-

solubility

DMSO: ≥20 mg/mL, H2O: insoluble, ethanol: 24 mg/mL

solubility

DMSO: 10 mg/mL (clear solution)

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.39 mg/mL, 0.1 M HCl: 3 mg/mL, DMSO: soluble, H2O: insoluble, ethanol: soluble

color

white to beige

color

white to beige

color

white to brown

color

white

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000086786
0000071707
0000071706
0000027392
0000027393

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Global Trade Item Number

SKUGTIN
L135-10MG04061832091716
L135-50MG04061832091723

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