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L131

L-745,870 hydrochloride

Synonym(s):

3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine hydrochloride

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Pack SizeSKUAvailabilityPrice
5 mg

Estimated to ship onJune 16, 2026fromMILWAUKEE

$352.00
25 mg

Estimated to ship onJune 16, 2026fromMILWAUKEE

$1,010.00
$858.50

About This Item

Empirical Formula (Hill Notation):
C18H19ClN4 · HCl
CAS Number:
1173023-36-3
Molecular Weight:
363.28
NACRES:
NA.77
PubChem Substance ID:
24277918
UNSPSC Code:
12352200
MDL number:
MFCD01529971
Form:
solid

$352.00

Estimated to ship onJune 16, 2026Details

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form

solid

Quality Segment

100

color

white

solubility

H2O: 0.2 mg/mL, ethanol: 1.4 mg/mL, 0.1 M HCl: 5.5 mg/mL

SMILES string

Cl.Clc1ccc(cc1)N2CCN(CC2)Cc3c[nH]c4ncccc34

InChI

1S/C18H19ClN4.ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;/h1-7,12H,8-11,13H2,(H,20,21);1H

InChI key

GFFJYISJZJIKAF-UHFFFAOYSA-N

Gene Information

human ... DRD4(1815)

Biochem/physiol Actions

Selective D4 dopamine receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold under license from Merck & Co., Inc., Kenilworth, NJ, U.S. for use solely for preclinical researchy purposes (i.e., not for the administration to or other use in humans).

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This Item
U101G119A9736
L-745,870 hydrochloride

Sigma-Aldrich

L131

L-745,870 hydrochloride

5-Methylurapidil solid

Sigma-Aldrich

U101

5-Methylurapidil

GYKI 52466 hydrochloride solid

Sigma-Aldrich

G119

GYKI 52466 hydrochloride

A-438079 hydrochloride hydrate ≥98% (HPLC)

Sigma-Aldrich

A9736

A-438079 hydrochloride hydrate

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: 0.2 mg/mL, 0.1 M HCl: 5.5 mg/mL, ethanol: 1.4 mg/mL

solubility

H2O: 0.4 mg/mL, 0.1 M HCl: 3.8 mg/mL

solubility

DMSO: 0.39 mg/mL, ethanol: 0.4 mg/mL, 0.1 M HCl: 0.68 mg/mL, methanol: 1 mg/mL, H2O: >10 mg/mL

solubility

DMSO: 20 mg/mL, clear

color

white

color

white

color

yellow

color

white to beige

Gene Information

human ... DRD4(1815)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Gene Information

human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)

Gene Information

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
127H4686V

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Global Trade Item Number

SKUGTIN
L131-25MG04061832091693
L131-5MG04061833949344

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