H4002

DL-3-Hydroxynorvaline

≥98% (TLC)

• Synonym(s): HNV, α-Amino-β-hydroxyvaleric acid, 2-Amino-3-hydroxypentanoic acid, 3-Hydroxy-2-aminopentanoic acid, DL-β-Hydroxynorvaline
• Empirical Formula (Hill Notation): C₅H₁₁NO₃
• CAS Number: 2280-42-4
• Molecular Weight: 133.15
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895609
• NACRES: NA.26
• Beilstein/REAXYS Number: 1722350
• MDL number: MFCD00010516

Properties

• Product Name: DL-3-Hydroxynorvaline, ≥98% (TLC)
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white
• application(s): cell analysis
• storage temp.: −20°C
• SMILES string: CCC(O)C(N)C(O)=O
• InChI: 1S/C5H11NO3/c1-2-3(7)4(6)5(8)9/h3-4,7H,2,6H2,1H3,(H,8,9)
• InChI key: LGVJIYCMHMKTPB-UHFFFAOYSA-N

Description

Biochem/physiol Actions

3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H315,H318,H335
• pcodes: P280 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves